1,8-Naphthyridine-3-carboxamide, 1,2-dihydro-N-(2-(dimethylamino)ethyl )-4-hydroxy-2-oxo-1-phenyl-

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Names

[ CAS No. ]:
138304-93-5

[ Name ]:
1,8-Naphthyridine-3-carboxamide, 1,2-dihydro-N-(2-(dimethylamino)ethyl )-4-hydroxy-2-oxo-1-phenyl-

Chemical & Physical Properties

[ Density]:
1.333g/cm3

[ Boiling Point ]:
539.6ºC at 760mmHg

[ Molecular Formula ]:
C19H20N4O3

[ Molecular Weight ]:
352.38700

[ Flash Point ]:
280.1ºC

[ Exact Mass ]:
352.15400

[ PSA ]:
87.46000

[ LogP ]:
1.77360

[ Vapour Pressure ]:
1.78E-12mmHg at 25°C

[ Index of Refraction ]:
1.648

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QN2790590
CHEMICAL NAME :
1,8-Naphthyridine-3-carboxamide, 1,2-dihydro-N-(2-(dimethylamino)ethyl)-4-hydroxy-2-ox o-1- phenyl-
CAS REGISTRY NUMBER :
138304-93-5
LAST UPDATED :
199806
DATA ITEMS CITED :
2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #5126341
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #5126341

Synthetic Route

Click to get detail synthetic route

Related Compounds

  • 1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-1-ethenyl-6-fluoro-4- oxo-7-(1-piperazinyl)-,monohydrochloride
  • 1,8-Naphthyridine-2-methanamine,N-methyl-(9CI)
  • 1,8-Naphthyridine-3-carboxamide, 1,2-dihydro-4-hydroxy-2-oxo-1-phenyl- N-4-pyridinyl-, hydrate (5:3)
  • 1,8-Naphthyridine-3-carboxylicacid,6-chloro-4-hydroxy-,ethylester(9CI)
  • 5-(2-oxo-1-phenyl-1,8-naphthyridin-3-yl)pentanoic acid
  • 1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-6-fluoro-1-(2-fluoroe thyl)-4-oxo-7-(1-piperazinyl)-
  • 1-[1-(butan-2-yl)-3-methyl-1H-pyrazol-5-yl]ethan-1-one
  • 4-[(Propan-2-yloxy)methyl]oxane-4-carbaldehyde
  • 1-[(Furan-3-yl)methyl]-2,2-dimethylcyclopropane-1-carbaldehyde
  • 1-(2-cyclopropyl-2-hydroxyethyl)-5-methyl-1H-1,2,3-triazole-4-carbaldehyde
  • 9-Methyl-5-(oxan-4-yl)-1-oxa-4-azaspiro[5.5]undecane
  • 3-Amino-4-(1-methylpyrrolidin-2-yl)butan-1-ol
  • 2-[1-(Pent-1-en-1-yl)cyclopropyl]ethan-1-amine
  • 2-{[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-methylpentanamido]methyl}pentanoic acid
  • 5-{[Cyclopropyl(methyl)amino]methyl}piperidine-3-carboxylic acid
  • 2,2,2-Trifluoro-1-(5-fluoro-3-methylbenzofuran-2-yl)ethan-1-amine
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