1,8-Naphthyridine-3-carboxamide, 1,2-dihydro-N-(2-(dimethylamino)ethyl )-4-hydroxy-2-oxo-1-phenyl-

Modify Date: 2025-09-21 17:04:00

1,8-Naphthyridine-3-carboxamide, 1,2-dihydro-N-(2-(dimethylamino)ethyl )-4-hydroxy-2-oxo-1-phenyl- Structure
1,8-Naphthyridine-3-carboxamide, 1,2-dihydro-N-(2-(dimethylamino)ethyl )-4-hydroxy-2-oxo-1-phenyl- structure
 Common Name 1,8-Naphthyridine-3-carboxamide, 1,2-dihydro-N-(2-(dimethylamino)ethyl )-4-hydroxy-2-oxo-1-phenyl-
CAS Number 138304-93-5 Molecular Weight 352.38700
Density 1.333g/cm3 Boiling Point 539.6ºC at 760mmHg
Molecular Formula C19H20N4O3 Melting Point N/A
MSDS N/A Flash Point 280.1ºC

 Names

Name N-[2-(dimethylamino)ethyl]-4-hydroxy-2-oxo-1-phenyl-1,8-naphthyridine-3-carboxamide

 Chemical & Physical Properties

Density 1.333g/cm3
Boiling Point 539.6ºC at 760mmHg
Molecular Formula C19H20N4O3
Molecular Weight 352.38700
Flash Point 280.1ºC
Exact Mass 352.15400
PSA 87.46000
LogP 1.77360
Vapour Pressure 1.78E-12mmHg at 25°C
Index of Refraction 1.648

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QN2790590
CHEMICAL NAME :
1,8-Naphthyridine-3-carboxamide, 1,2-dihydro-N-(2-(dimethylamino)ethyl)-4-hydroxy-2-ox o-1- phenyl-
CAS REGISTRY NUMBER :
138304-93-5
LAST UPDATED :
199806
DATA ITEMS CITED :
2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #5126341
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #5126341

 Synthetic Route

ETHYL 4-HYDROXY-2-OXO-1-PHENYL-1,2-DIHYDRO-1,8-NAPHTHYRIDINE-3-CARBOXYLATE structure

ETHYL 4-HYDROXY...

CAS#:138305-20-1

1,1-Dimethylethylenediamine structure

1,1-Dimethyleth...

CAS#:108-00-9

~64%

1,8-Naphthyridine-3-carboxamide, 1,2-dihydro-N-(2-(dimethylamino)ethyl )-4-hydroxy-2-oxo-1-phenyl- Structure

1,8-Naphthyridi...

CAS#:138304-93-5

Literature: Kuroda; Suzuki; Tamura; Ohmori; Hosoe Journal of Medicinal Chemistry, 1992 , vol. 35, # 6 p. 1130 - 1136
1-PHENYL-1H-PYRIDO[2,3-D][1,3]OXAZINE-2,4-DIONE structure

1-PHENYL-1H-PYR...

CAS#:138305-19-8

~%

1,8-Naphthyridine-3-carboxamide, 1,2-dihydro-N-(2-(dimethylamino)ethyl )-4-hydroxy-2-oxo-1-phenyl- Structure

1,8-Naphthyridi...

CAS#:138304-93-5

Literature: Kuroda; Suzuki; Tamura; Ohmori; Hosoe Journal of Medicinal Chemistry, 1992 , vol. 35, # 6 p. 1130 - 1136
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Chemsrc provides CAS#:138304-93-5 MSDS, density, melting point, boiling point, structure, etc. Its name is 1,8-Naphthyridine-3-carboxamide, 1,2-dihydro-N-(2-(dimethylamino)ethyl )-4-hydroxy-2-oxo-1-phenyl->> amp version: 1,8-Naphthyridine-3-carboxamide, 1,2-dihydro-N-(2-(dimethylamino)ethyl )-4-hydroxy-2-oxo-1-phenyl-

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