Capsazepine

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Names

[ Name ]:
Capsazepine

[Synonym ]:
N-[2-(4-Chlorophenyl)ethyl]-1,3,4,5-tetrahydro-7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide
MFCD00153778
2H-2-Benzazepine-2-carbothioamide, N-[2-(4-chlorophenyl)ethyl]-1,3,4,5-tetrahydro-7,8-dihydroxy-
N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide
Capsazepine
N-[2-(4-Chlorophenyl)ethyl]-7,8-dihydroxy-1,3,4,5-tetrahydro-2H-2-benzazepine-2-carbothioamide

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
581.1±60.0 °C at 760 mmHg

[ Melting Point ]:
155-157°C

[ Molecular Formula ]:
C₁₉H₂₁ClN₂O₂S

[ Molecular Weight ]:
376.900

[ Flash Point ]:
305.3±32.9 °C

[ Exact Mass ]:
376.101227

[ PSA ]:
87.82000

[ LogP ]:
3.50

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.672

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
methanol: soluble

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
2811

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1(a)

Articles

Cross-talk between alpha1D-adrenoceptors and transient receptor potential vanilloid type 1 triggers prostate cancer cell proliferation.

BMC Cancer 14 , 921, (2014)

There is evidence that calcium (Ca(2+)) increases the proliferation of human advanced prostate cancer (PCa) cells but the ion channels involved are not fully understood. Here, we investigated the corr...

Cannabinoids increase lung cancer cell lysis by lymphokine-activated killer cells via upregulation of ICAM-1.

Biochem. Pharmacol. 92(2) , 312-25, (2014)

Cannabinoids have been shown to promote the expression of the intercellular adhesion molecule 1 (ICAM-1) on lung cancer cells as part of their anti-invasive and antimetastatic action. Using lung cance...

Piperine inhibits the growth and motility of triple-negative breast cancer cells.

Cancer Lett. 357(1) , 129-40, (2014)

Piperine, an alkaloid from black pepper, is reported to have anticancer activities. In this study, we investigated the effect of piperine on the growth and motility of triple-negative breast cancer (T...

2-(1-Amino-4,4-difluorocyclohexyl)-6-ethoxyphenol
2,2-Dimethyl-3-(6-methylpyridin-3-yl)propanal
4-(2,6-dimethoxy-4-methylphenyl)-1H-pyrazole
2-Methyl-5-(4-phenylcyclohexyl)-1,3,2lambda5-dioxaphosphinane-2-thione
Benzamide, N-[5-amino-1-[(2-naphthalenylamino)carbonyl]pentyl]-, (S)-
2,6-Dimethyl-4-oxo-N-[2-(1-piperidinyl)phenyl]-4H-pyran-3-carboxamide
1-Ethyl-4-[1,2,3,6-tetrahydro-1-(phenylmethyl)-4-pyridinyl]piperazine
{1-[(4-Cyclopropylphenyl)methyl]cyclopropyl}methanamine
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Tert-butyl 3-formyl-4-propylpyrrolidine-1-carboxylate

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