Simvastatin ammonium salt

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Names

[ Name ]:
Simvastatin ammonium salt

[Synonym ]:
Simvastatin hydroxy acid ammonium salt
Simvastatin ammonium salt
Ammonium (3R,5R)-7-{(1S,2S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydro-1-naphthalenyl}-3,5-dihydroxyheptanoate
Simvastatin carboxylic acid ammonium salt
Tenivastatin ammonium salt
azanium,(3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-(2,2-dimethylbutanoyloxy)-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
1-Naphthaleneheptanoate, 8-(2,2-dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-, ammonium salt, (βR,δR,1S,2S,6R,8S,8aR)- (1:1)

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₄₃NO₆

[ Molecular Weight ]:
453.612

[ Exact Mass ]:
453.309052

[ PSA ]:
107.30000

[ LogP ]:
4.42960

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H351-H360-H412

[ Precautionary Statements ]:
P201-P273-P281-P308 + P313

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

Articles

Simvastatin decreases steroid production in the H295R cell line and decreases steroids and FSH in female rats.

Reprod. Toxicol. 58 , 174-83, (2015)

Endocrine modulating effects of Simvastatin (SV) and its metabolite, Simvastatin β-hydroxy acid (SVA), were investigated in H295R cells and in female Sprague-Dawley (SPRD) rats. H295R cells were expos...