Simvastatin ammonium salt

Simvastatin ammonium salt Structure
Simvastatin ammonium salt structure
Common Name Simvastatin ammonium salt
CAS Number 139893-43-9 Molecular Weight 453.612
Density N/A Boiling Point N/A
Molecular Formula C25H43NO6 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS08
GHS08
Signal Word Danger

Simvastatin decreases steroid production in the H295R cell line and decreases steroids and FSH in female rats.

Reprod. Toxicol. 58 , 174-83, (2015)

Endocrine modulating effects of Simvastatin (SV) and its metabolite, Simvastatin β-hydroxy acid (SVA), were investigated in H295R cells and in female Sprague-Dawley (SPRD) rats. H295R cells were exposed to SV and SVA concentrations from 0 to 10μM for 48h. Fou...