diethylmaleate
Suppliers
Names
[ CAS No. ]:
141-05-9
[ Name ]:
diethylmaleate
[Synonym ]:
cis-Diethyl maleate
MFCD00009191
diethyl L-malic ester
Diethyl L-(-)-Malate
(S)-(-)-Aepfelsaeure-diethylester
cis-Propenoic acid diethyl ester
Maleic acid, diethyl ester
EINECS 205-451-9
(S)-malic acid diethyl ester
diethylmaleate
2-Butenedioic acid, diethyl ester, (2Z)-
Diethyl (2Z)-2-butenedioate
Diethyl (2Z)-but-2-enedioate
cis-EtO2CCH=CHCO2Et
L-(-)-Malic Acid Diethyl Ester
(S)-(-)-diethyl 2-hydroxybutandioate
diethyl (Z)-but-2-enedioate
diethyl (2Z)but-2-ene-1,4-dioate
1,4-diethyl (2Z)-but-2-enedioate
2-Butenedioic acid (2Z)-, diethyl ester
2-Butenedioic acid (Z)-, diethyl ester
maleic acid diethyl ester
Ethyl Maleate
(2S)-2-hydroxybutanedioic acid diethylester
Diethyl maleate
diethyl (S)-malate
(Z)-2-Butenedioic acid diethyl ester
Irsogladine Impurity 3
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
214.0±0.0 °C at 760 mmHg
[ Melting Point ]:
−10 °C(lit.)
[ Molecular Formula ]:
C8H12O4
[ Molecular Weight ]:
172.178
[ Flash Point ]:
93.3±0.0 °C
[ Exact Mass ]:
172.073563
[ PSA ]:
52.60000
[ LogP ]:
1.68
[ Vapour density ]:
5.93 (vs air)
[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.443
[ Stability ]:
Stable. Combustible. Incompatible with oxidizing agents, bases, acids, reducing agents.
[ Water Solubility ]:
insoluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- ON1225000
- CHEMICAL NAME :
- Maleic acid, diethyl ester
- CAS REGISTRY NUMBER :
- 141-05-9
- BEILSTEIN REFERENCE NO. :
- 1100825
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C8-H12-O4
- MOLECULAR WEIGHT :
- 172.20
- WISWESSER LINE NOTATION :
- 2OV1U1VO2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Open irritation test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3070 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation Gastrointestinal - changes in structure or function of salivary glands Gastrointestinal - hypermotility, diarrhea
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 4 mL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 8700 nmol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 182,135,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 1 mg/m3;Skin JAN 1993
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H317-H319-H412
[ Precautionary Statements ]:
P273-P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R43
[ Safety Phrases ]:
S26-S36/37-S37-S24
[ RIDADR ]:
3334
[ WGK Germany ]:
2
[ RTECS ]:
ON1225000
[ HS Code ]:
29171990
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2917190090
[ Summary ]:
2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
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