1-Boc-4-(2-oxo-ethyl)piperidine

Suppliers

Names

[ Name ]:
1-Boc-4-(2-oxo-ethyl)piperidine

[Synonym ]:
1-Boc-4-(2-oxo-ethyl)piperidine
1-Piperidinecarboxylic acid, 4-(2-oxoethyl)-, 1,1-dimethylethyl ester
4-(2-Oxoethyl)piperidine-1-carboxylic Acid tert-Butyl Ester
tert-Butyl 4-(2-oxoethyl)piperidine-1-carboxylate
2-Methyl-2-propanyl 4-(2-oxoethyl)-1-piperidinecarboxylate
2-(N-BOC-4-piperidinyl)acetaldehyde

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
318.1±15.0 °C at 760 mmHg

[ Melting Point ]:
38-42ºC

[ Molecular Formula ]:
C₁₂H₂₁NO₃

[ Molecular Weight ]:
227.300

[ Flash Point ]:
146.2±20.4 °C

[ Exact Mass ]:
227.152145

[ PSA ]:
46.61000

[ LogP ]:
1.45

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.467

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

1-Boc-4-(2-hydroxyethyl)piperidine
Oxalyl chloride
N-Boc-4-ethyl piperidinecarboxylate
tert-butyl 4-(2-oxoethylidene)piperidine-1-carboxylate
2-(4-Piperidinyl)ethanol
4-Pyridinylacetic acid
4-(2-Ethoxy-2-oxoethylidene)-1-piperidinecarboxylic acid tert-butyl ester
Di-tert-butyl dicarbonate
4-(Carboxymethyl)pyridinium chloride
1-Boc-4-piperidylacetic acid

DownStream

1-BOC-4-(4-METHOXY-4-OXO-2-BUTENYL)PIPERIDINE
tert-butyl 4-(1-bromo-2-oxoethyl)piperidine-1-carboxylate
tert-Butyl 4-(2-(methylamino)ethyl)piperidine-1-carboxylate
1-N-Boc-4-(3-Cbz-amino-3-methoxycarbonylallyl)piperidine
tert-butyl 4-(3-hydroxyprop-1-en-2-yl)piperidine-1-carboxylate
1-Boc-4-(4-Bromobutyl)piperidine
4-(1-Boc-4-piperidyl)-1-butanol
N-Boc-4-Piperidin-4-yl-butyric acid
1-BOC-4-(CYANOMETHYL)PIPERIDINE
tert-Butyl 4-(prop-2-yn-1-yl)piperidine-1-carboxylate

Articles

Enantioselective organo-SOMO catalysis: the alpha-vinylation of aldehydes.

J. Am. Chem. Soc. 130 , 398, (2008)

Tetrahedron Lett. 47 , 2515, (2006)

1-BOC-4-(2-METHANESULFONYLOXY-ETHYL)-PIPERIDINE
1-Boc-4-(2-oxo-piperidin-1-ylmethyl)piperidine
1-BOC-4-(2-OXO-3-PYRIDIN-4-YL-PROPYL)-PIPERIDINE
1-BOC-4-(2-CBZ-AMINO-2-METHOXYCARBONYL-ETHYL)PIPERIDINE
(R)-1-Boc-2-(2-Oxoethyl)Piperidine
(S)-1-Boc-2-(2-Oxoethyl)Piperidine
2-fluoro-N-{[4-(morpholin-4-yl)thian-4-yl]methyl}benzamide
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
4-Amino-1-(butan-2-yl)-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
Di-tert-butyl (4-bromoquinolin-2-yl)iminodicarbonate
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
1-(Chloromethyl)-3-(3-fluoro-2-methylphenyl)bicyclo[1.1.1]pentane
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide