FGIN-1-27

Names

[ CAS No. ]:
142720-24-9

[ Name ]:
FGIN-1-27

[Synonym ]:
MFCD00467704
Fgin 1 27
Lopac-D-8555
Tocris-0658
N,N-Dihexyl-2-(4-fluorophenyl)indole-3-acetamide

Chemical & Physical Properties

[ Density]:
1.073g/cm3

[ Boiling Point ]:
608.3ºC at 760mmHg

[ Molecular Formula ]:
C₂₈H₃₇FN₂O

[ Molecular Weight ]:
436.60500

[ Flash Point ]:
321.7ºC

[ Exact Mass ]:
436.28900

[ PSA ]:
36.10000

[ LogP ]:
7.50570

[ Vapour Pressure ]:
9.6E-15mmHg at 25°C

[ Index of Refraction ]:
1.562

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Design, synthesis and structure-affinity relationships of aryloxyanilide derivatives as novel peripheral benzodiazepine receptor ligands.

Bioorg. Med. Chem. 12(2) , 423-38, (2004)

Since the peripheral benzodiazepine receptor (PBR) has been primarily found as a high-affinity binding site for diazepam in rat kidney, numerous studies of it have been performed. However, the physiol...

Translocator protein (18 kDa) as a pharmacological target in adipocytes to regulate glucose homeostasis.

Biochem. Pharmacol. 97 , 99-110, (2015)

As a major regulator in obesity and its associated metabolic complications, the proper functioning of adipocytes is crucial for health maintenance, thus serving as an important target for the developm...

Ligands of the peripheral benzodiazepine receptor induce apoptosis and cell cycle arrest in oesophageal cancer cells: involvement of the p38MAPK signalling pathway.

Br. J. Cancer 89(3) , 564-72, (2003)

Specific ligands of the peripheral benzodiazepine receptor (PBR) are known to induce apoptosis and cell cycle arrest in oesophageal cancer cells. However, the underlying mechanisms are still unknown. ...