PF 05089771

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Names

[ CAS No. ]:
1430806-04-4

[ Name ]:
PF 05089771

[Synonym ]:
4-[2-(3-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-4-thiazolyl-benzenesulfonamide 4-methylbenzenesulfonate (1:1)
PF-05089771
4-[2-(5-Amino-1H-pyrazol-4-yl)-4-chloro-phenoxy]-5-chloro-2-fluoro-N-thiazol-4-yl-benzenesulfonamide p-toluene sulfonate salt
PF-05089771 p-toluene sulfonate salt
MFCD30146405
4-[2-(3-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-(1,3-thiazol-4-yl)benzenesulfonamide 4-methylbenzenesulfonate (1:1)
Benzenesulfonamide, 4-[2-(3-amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-4-thiazolyl-, 4-methylbenzenesulfonate (1:1)
Pf-05089771 Tosylate

Chemical & Physical Properties

[ Molecular Formula ]:
C18H12Cl2FN5O3S2

[ Molecular Weight ]:
672.556

[ Exact Mass ]:
670.993652

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release.

PLoS ONE 11(4) , e0152405, (2016)

Human genetic studies show that the voltage gated sodium channel 1.7 (Nav1.7) is a key molecular determinant of pain sensation. However, defining the Nav1.7 contribution to nociceptive signalling has ...


More Articles

Related Compounds

  • PF 05089771
  • PF-06471553
  • PF-05085727
  • PF-03463275
  • PF-06815189
  • PF-06869206
  • 4-Phenyl-1-(4-(pyrazin-2-yloxy)piperidin-1-yl)butan-1-one
  • 8-Fluoro-2-(3-thiomorpholin-4-ylpropanoyl)-1,3,4,5-tetrahydrobenzo[c][1,6]naphthyridin-6-one
  • 1-Cyclopentyl-3-(5-(furan-2-carbonyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)urea
  • N,N-dimethyl-4-(4-(pyrazin-2-yloxy)piperidine-1-carbonyl)benzenesulfonamide
  • 1-Cyclopentyl-3-(5-(5-methylisoxazole-3-carbonyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)urea
  • 1-(1H-indol-3-yl)-2-(4-(pyrazin-2-yloxy)piperidin-1-yl)ethane-1,2-dione
  • Ethyl 4-(pyrazin-2-yloxy)piperidine-1-carboxylate
  • 1-Cyclopentyl-3-(5-(2-(4-(isopropylsulfonyl)phenyl)acetyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)urea
  • 1-(4-Chlorophenyl)-4-(4-(pyrazin-2-yloxy)piperidine-1-carbonyl)pyrrolidin-2-one
  • 1-(3,4-Dimethylphenyl)-4-[4-(pyrazin-2-yloxy)piperidine-1-carbonyl]pyrrolidin-2-one
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