PF 05089771

PF 05089771 Structure
PF 05089771 structure
Common Name PF 05089771
CAS Number 1430806-04-4 Molecular Weight 672.556
Density N/A Boiling Point N/A
Molecular Formula C18H12Cl2FN5O3S2 Melting Point N/A
MSDS USA Flash Point N/A

Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release.

PLoS ONE 11(4) , e0152405, (2016)

Human genetic studies show that the voltage gated sodium channel 1.7 (Nav1.7) is a key molecular determinant of pain sensation. However, defining the Nav1.7 contribution to nociceptive signalling has been hampered by a lack of selective inhibitors. Here we re...