![]() PF 05089771 structure
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Common Name | PF 05089771 | ||
---|---|---|---|---|
CAS Number | 1430806-04-4 | Molecular Weight | 672.556 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C18H12Cl2FN5O3S2 | Melting Point | N/A | |
MSDS | USA | Flash Point | N/A |
Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release.
PLoS ONE 11(4) , e0152405, (2016) Human genetic studies show that the voltage gated sodium channel 1.7 (Nav1.7) is a key molecular determinant of pain sensation. However, defining the Nav1.7 contribution to nociceptive signalling has been hampered by a lack of selective inhibitors. Here we re... |
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