4'-[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carbonitrile

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Names

[ CAS No. ]:
144702-27-2

[ Name ]:
4'-[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carbonitrile

[Synonym ]:
BIP007
2-Descarboxy-2-cyano Telmisartan
Telmisartan Impurity G
UNII-A8M0GXG1XV
(1,1'-Biphenyl)-2-carbonitrile,4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)
4'-[[2-n-propyl-4-methyl-6-(1-methylbenzimidazol-2-yl)-benzimidazol-1-yl]-methyl]-2-cyano-biphenyl
4'-[[2-n-propyl-4-methyl-6-(1-methyl-benzimidazol-2-yl)-1H-benzimidazol-1-yl]-methyl]-2-cyano-biphenyl
4'-{[2-n-propyl-4-methyl-6-(1-methylbenzoimidazol-2-yl)benzoimidazol-1-yl]methyl}-2-cyanobiphenyl
Telmisartan impurity G [EP]
2-cyano-4'-[2''-n-propyl-4''-methyl-6''-(1'''-methylbenzimidazole-2'''-yl)benzimidazole-1''-ylmethyl]biphenyl
2-cyano-4'-(2''-n-propyl-4''-methyl-6''-(1'''-methylbenzimidazol-2'''-yl)benzimidazol-1''-ylmethyl)biphenyl
4'-[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carbonitrile
Telmisartan Impurity 7

Chemical & Physical Properties

[ Density]:
1.188g/cm3

[ Boiling Point ]:
775.126ºC at 760 mmHg

[ Melting Point ]:
181.2-182.1 ºC

[ Molecular Formula ]:
C33H29N5

[ Molecular Weight ]:
495.61700

[ Flash Point ]:
422.581ºC

[ Exact Mass ]:
495.24200

[ PSA ]:
59.43000

[ LogP ]:
7.43788

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.664

[ Water Solubility ]:
Insuluble (5.0E-6 g/L) (25 ºC)

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Bromomethyl-2-cyanobiphenyl
  • 2-n-Propyl-4-methyl-6-(1-methylbenzimidazole-2-yl)benzimidazole
  • 4-(2'-cyanophenyl)benzyl chloride
  • N-[2-[[4-(2-cyanophenyl)phenyl]methylamino]-6-methyl-4-(1-methylbenzimidazol-2-yl)phenyl]butanamide
  • 7-methyl-N-(2-methylamino)-phenyl-2-propyl-3-(2'-cyano-4"-ylmethylbiphenyl)-3H-benzimidazole-5-carboxamide
  • 3-[[4-(2-cyanophenyl)phenyl]methyl]-7-methyl-2-propylbenzimidazole-5-carboxylic acid
  • N-Methyl-1,2-benzenediamine dihydrochloride
  • N-(2-aminophenyl)-3-[[4-(2-cyanophenyl)phenyl]methyl]-N,7-dimethyl-2-propylbenzimidazole-5-carboxamide
  • 4'-Methyl-2-cyanobiphenyl

DownStream

  • Telmisartan
  • Telmisartan Amide

Related Compounds

  • 1-(Oxolan-3-yl)cyclopropane-1-carbaldehyde
  • n'-Hydroxy-4-(4-methylpiperazin-1-yl)pyridine-2-carboximidamide
  • 4-[1-(6-Cyanopyridin-3-yl)sulfonylpiperidin-2-yl]butanoic acid
  • 1-(3-Hydroxyphenyl)-3-oxocyclobutane-1-carbonitrile
  • 1-Chloro-1-(3-(chloromethyl)-4-iodophenyl)propan-2-one
  • N-(1-Sulfamoylpiperidin-4-yl)prop-2-enamide
  • 7-(3,4-Dihydro-1H-isochromene-6-carbonyl)-1,7-diazaspiro[3.5]nonan-2-one
  • 5-Chloro-2-(2-fluorophenyl)-6-methyl-4(3H)-pyrimidinone
  • N-[4-Fluoro-3-(prop-2-enoylamino)phenyl]bicyclo[6.1.0]nonane-9-carboxamide
  • N-[[4-(Trifluoromethyl)pyridin-3-yl]methyl]prop-2-enamide
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