sodium dehydrocholate
Suppliers
Names
[ CAS No. ]:
145-41-5
[ Name ]:
sodium dehydrocholate
[Synonym ]:
Dycholium
Dehydrocholic acid sodium salt
3,7,12-Trioxo-5b-cholan-24-oic Acid Monosodium Salt
Biliton
Biliron
3,7,12-Trioxo-5b-cholan-24-oic Acid Sodium Salt
Natriumdehydrocholat
Decholin sodium salt
sodium dehydrocholate
(5b)-3,7,12-Trioxocholan-24-oic Acid Sodium Salt
SodiuMDehydrocholic
Sodium (5β)-3,7,12-trioxocholan-24-oate
Carachol
dilabilsodium
decholinsodium
MFCD00150750
Sodium 3,7,12-Trioxo-5b-cholan-24-oate
Cholan-24-oic acid, 3,7,12-trioxo-, sodium salt, (5β)-
Sodium 3,7,12-triketocholanate
Dehydrocholate sodium
Sodium 3,7,12-Trioxo-5b-cholanate
dehydrocholic acid monosodium salt
Cholan-24-oic acid, 3,7,12-trioxo-, sodium salt, (5β)- (1:1)
Dilabil sodium
Sodium 3,7,12-trioxo-5β-cholan-24-oate
Decholin sodium
EINECS 205-652-1
decholinsodiumsalt
BILITON SODIUM SALT
Suprachol
Dehydrocholate (sodium)
Chemical & Physical Properties
[ Boiling Point ]:
581.5ºC at 760mmHg
[ Melting Point ]:
>300°C
[ Molecular Formula ]:
C24H33NaO5
[ Molecular Weight ]:
424.506
[ Flash Point ]:
319.5ºC
[ Exact Mass ]:
424.222565
[ PSA ]:
91.34000
[ LogP ]:
2.73860
[ Index of Refraction ]:
27 ° (C=5, H2O)
[ Water Solubility ]:
H2O: 0.1 M at 20 °C, clear, colorless
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- FZ2500000
- CHEMICAL NAME :
- 5-beta-Cholan-24-oic acid, 3,7,12-trioxo-, sodium salt
- CAS REGISTRY NUMBER :
- 145-41-5
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C24-H33-O5.Na
- MOLECULAR WEIGHT :
- 424.56
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3755 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GWXXBX German Offenlegungsschrift Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2630169
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 5,188,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2300 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
- REFERENCE :
- YOIZA3 Yonago Igaku Zasshi. Journal of the Yonago Medical Association. (c/o Tottori Daigaku Igakabu, 86 Nishi-machi, Yonago, Japan) V.1- 1948- Volume(issue)/page/year: 25,70,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 887 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- RPOBAR Research Progress in Organic-Biological and Medicinal Chemistry. (New York, NY) V.1-3, 1964-72. Discontinued. Volume(issue)/page/year: 2,280,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2150 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
- REFERENCE :
- YOIZA3 Yonago Igaku Zasshi. Journal of the Yonago Medical Association. (c/o Tottori Daigaku Igakabu, 86 Nishi-machi, Yonago, Japan) V.1- 1948- Volume(issue)/page/year: 25,70,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1480 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- RPOBAR Research Progress in Organic-Biological and Medicinal Chemistry. (New York, NY) V.1-3, 1964-72. Discontinued. Volume(issue)/page/year: 2,280,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1350 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
- REFERENCE :
- YOIZA3 Yonago Igaku Zasshi. Journal of the Yonago Medical Association. (c/o Tottori Daigaku Igakabu, 86 Nishi-machi, Yonago, Japan) V.1- 1948- Volume(issue)/page/year: 25,70,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1100 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
- REFERENCE :
- YOIZA3 Yonago Igaku Zasshi. Journal of the Yonago Medical Association. (c/o Tottori Daigaku Igakabu, 86 Nishi-machi, Yonago, Japan) V.1- 1948- Volume(issue)/page/year: 25,70,1974
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Cardiac - other changes Gastrointestinal - other changes Blood - other changes
- REFERENCE :
- ZGEMAZ Zeitschrift fuer die Gesamte Experimentelle Medizin. (Berlin, Fed. Rep. Ger.) V.1-139, 1913-65. For publisher information, see REXMAS. Volume(issue)/page/year: 52,779,1926
Safety Information
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
R22
[ Safety Phrases ]:
S22-S36
[ WGK Germany ]:
3
[ RTECS ]:
FZ2500000