Mastoparan 7 trifluoroacetate salt

[ Density]:
1.154g/cm3

[ Boiling Point ]:
1649.9ºC at 760mmHg

[ Molecular Formula ]:
C₆₇H₁₂₄N₁₈O₁₅

[ Molecular Weight ]:
1421.81

[ Flash Point ]:
951.6ºC

[ PSA ]:
644.54000

[ LogP ]:
5.49270

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.523

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[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Activation of GTP formation and high-affinity GTP hydrolysis by mastoparan in various cell membranes. G-protein activation via nucleoside diphosphate kinase, a possible general mechanism of mastoparan action.

Biochem. Pharmacol. 51 , 217-223, (1996)

The wasp venom, mastoparan (MP), is a direct activator of reconstituted pertussis toxin-sensitive G-proteins and of purified nucleoside diphosphate kinase (NDPK) [E.C. 2.6.4.6.]. In HL-60 membranes, M...

The heterotrimeric G-protein Gi is localized to the insulin secretory granules of beta-cells and is involved in insulin exocytosis.

J. Biol. Chem. 270 , 12869, (1995)

Mastoparan, a tetradecapeptide found in wasp venom that stimulates G-proteins, increases insulin secretion from beta-cells. In this study, we have examined the role of heterotrimeric G-proteins in mas...

Mastoparan may activate GTP hydrolysis by Gi-proteins in HL-60 membranes indirectly through interaction with nucleoside diphosphate kinase.

Biochemistry 304 , 377-383, (1994)

The wasp venom, mastoparan (MP), activates reconstituted pertussis toxin (PTX)-sensitive G-proteins in a receptor-independent manner. We studied the effects of MP and its analogue, mastoparan 7 (MP 7)...

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