Bismuth Subsalicylate
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Names
[ CAS No. ]:
14882-18-9
[ Name ]:
Bismuth Subsalicylate
[Synonym ]:
Bismuth(III) salicylate basic
Bismuth oxide salicylate
Bismuth Subsalicylate
4H-1,3,2-Benzodioxabismin-4-one, 2-hydroxy-
EINECS 238-953-1
MFCD00085368
Bismuth(III) subsalicylate
Bismuth, (2-hydroxybenzoato-O1,O2)oxo-
2-Hydroxy-4H-1,3,2-benzodioxabismin-4-one
Bismuth oxysalicylate
Pepto-Bismol
Chemical & Physical Properties
[ Boiling Point ]:
336.3ºC at 760mmHg
[ Melting Point ]:
>35ºC
[ Molecular Formula ]:
C7H5BiO4
[ Molecular Weight ]:
362.093
[ Flash Point ]:
144.5ºC
[ Exact Mass ]:
361.999176
[ PSA ]:
55.76000
[ LogP ]:
0.97400
[ Vapour Pressure ]:
4.45E-05mmHg at 25°C
[ Water Solubility ]:
Practically insoluble in water, alcoholSoluble in acid and alkali. Insoluble in cold water, ethanol, diethyl ether and n-octanol.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EB2985000
- CHEMICAL NAME :
- Bismuth, oxo(salicylato)-
- CAS REGISTRY NUMBER :
- 14882-18-9
- LAST UPDATED :
- 199504
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C7-H5-Bi-O4
- MOLECULAR WEIGHT :
- 362.10
- WISWESSER LINE NOTATION :
- QR BVO-BI-O
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Human - man
- DOSE/DURATION :
- 60 mg/kg/26W-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
- REFERENCE :
- AJCPAI American Journal of Clinical Pathology. (Lippincott/Harper, Journal Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1931- Volume(issue)/page/year: 14,392,1944
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 14480 ug/kg/9D-I
- TOXIC EFFECTS :
- Musculoskeletal - joints Skin and Appendages - dermatitis, allergic (after systemic exposure) Nutritional and Gross Metabolic - body temperature increase
- REFERENCE :
- ADSYAF Archives of Dermatology and Syphilology. (Chicago, IL) V.1-62, 1920-50. For publisher information, see ARDEAC. Volume(issue)/page/year: 41,1076,1940
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Human - man
- DOSE/DURATION :
- 17 mg/kg/5W-I
- TOXIC EFFECTS :
- Gastrointestinal - other changes
- REFERENCE :
- AJSGA3 American Journal of Syphilis, Gonorrhea and Venereal Diseases. (St. Louis, MO) V.20-38, 1936-54. Discontinued. Volume(issue)/page/year: 26,84,1942 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80378 No. of Facilities: 96 (estimated) No. of Industries: 1 No. of Occupations: 8 No. of Employees: 3666 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80378 No. of Facilities: 405 (estimated) No. of Industries: 2 No. of Occupations: 6 No. of Employees: 4036 (estimated) No. of Female Employees: 2022 (estimated)
Safety Information
[ Hazard Codes ]:
Xi
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
EB2985000