Bismuth Subsalicylate

Modify Date: 2025-08-30 16:39:45

Bismuth Subsalicylate structure	Common Name	Bismuth Subsalicylate
	CAS Number	14882-18-9	Molecular Weight	362.093
	Density	N/A	Boiling Point	336.3ºC at 760mmHg
	Molecular Formula	C₇H₅BiO₄	Melting Point	>35ºC
	MSDS	N/A	Flash Point	144.5ºC

Use of Bismuth Subsalicylate

Bismuth Subsalicylate is the active ingredient in Pepto-Bismol and inhibits prostaglandin G/H Synthase 1/2.Target: OthersBismuth Subsalicylate reduces inflammation/irritation of stomach and intestinal lining through inhibition of prostaglandin G/H Synthase 1/2 [1]. Bismuth Subsalicylate is the active ingredient in Pepto-Bismol, an anti-diarrhea medication and antacid. In the gastrointestinal tract, Bismuth Subsalicylate is converted to salicylic acid and insoluble bismuth salts [2]. Bismuth subsalicylate treatment for 8 weeks is safe and well tolerated. This regimen appears to be efficacious for the treatment of microscopic colitis and is worthy of further study in a controlled trial [3].

Name	bismuth subsalicylate
Synonym	More Synonyms

Description	Bismuth Subsalicylate is the active ingredient in Pepto-Bismol and inhibits prostaglandin G/H Synthase 1/2.Target: OthersBismuth Subsalicylate reduces inflammation/irritation of stomach and intestinal lining through inhibition of prostaglandin G/H Synthase 1/2 [1]. Bismuth Subsalicylate is the active ingredient in Pepto-Bismol, an anti-diarrhea medication and antacid. In the gastrointestinal tract, Bismuth Subsalicylate is converted to salicylic acid and insoluble bismuth salts [2]. Bismuth subsalicylate treatment for 8 weeks is safe and well tolerated. This regimen appears to be efficacious for the treatment of microscopic colitis and is worthy of further study in a controlled trial [3].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> PGE synthase Research Areas >> Neurological Disease
References	[1]. Sox, T.E. and C.A. Olson, Binding and killing of bacteria by bismuth subsalicylate. Antimicrob Agents Chemother, 1989. 33(12): p. 2075-82. [2]. Bierer, D.W., Bismuth subsalicylate: history, chemistry, and safety. Rev Infect Dis, 1990. 12 Suppl 1: p. S3-8. [3]. Fine, K.D. and E.L. Lee, Efficacy of open-label bismuth subsalicylate for the treatment of microscopic colitis. Gastroenterology, 1998. 114(1): p. 29-36.

Description

Related Catalog

Signaling Pathways >> Immunology/Inflammation >> PGE synthase

Research Areas >> Neurological Disease

References

[1]. Sox, T.E. and C.A. Olson, Binding and killing of bacteria by bismuth subsalicylate. Antimicrob Agents Chemother, 1989. 33(12): p. 2075-82.

[2]. Bierer, D.W., Bismuth subsalicylate: history, chemistry, and safety. Rev Infect Dis, 1990. 12 Suppl 1: p. S3-8.

[3]. Fine, K.D. and E.L. Lee, Efficacy of open-label bismuth subsalicylate for the treatment of microscopic colitis. Gastroenterology, 1998. 114(1): p. 29-36.

Boiling Point	336.3ºC at 760mmHg
Melting Point	>35ºC
Molecular Formula	C₇H₅BiO₄
Molecular Weight	362.093
Flash Point	144.5ºC
Exact Mass	361.999176
PSA	55.76000
LogP	0.97400
Vapour Pressure	4.45E-05mmHg at 25°C
Water Solubility	Practically insoluble in water, alcoholSoluble in acid and alkali. Insoluble in cold water, ethanol, diethyl ether and n-octanol.

Bismuth Subsalicylate MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EB2985000

CHEMICAL NAME :: Bismuth, oxo(salicylato)-

CAS REGISTRY NUMBER :: 14882-18-9

LAST UPDATED :: 199504

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C7-H5-Bi-O4

MOLECULAR WEIGHT :: 362.10

WISWESSER LINE NOTATION :: QR BVO-BI-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Human - man

DOSE/DURATION :: 60 mg/kg/26W-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)

REFERENCE :: AJCPAI American Journal of Clinical Pathology. (Lippincott/Harper, Journal Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1931- Volume(issue)/page/year: 14,392,1944

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Human - woman

DOSE/DURATION :: 14480 ug/kg/9D-I

TOXIC EFFECTS :: Musculoskeletal - joints Skin and Appendages - dermatitis, allergic (after systemic exposure) Nutritional and Gross Metabolic - body temperature increase

REFERENCE :: ADSYAF Archives of Dermatology and Syphilology. (Chicago, IL) V.1-62, 1920-50. For publisher information, see ARDEAC. Volume(issue)/page/year: 41,1076,1940

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Human - man

DOSE/DURATION :: 17 mg/kg/5W-I

TOXIC EFFECTS :: Gastrointestinal - other changes

REFERENCE :: AJSGA3 American Journal of Syphilis, Gonorrhea and Venereal Diseases. (St. Louis, MO) V.20-38, 1936-54. Discontinued. Volume(issue)/page/year: 26,84,1942 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80378 No. of Facilities: 96 (estimated) No. of Industries: 1 No. of Occupations: 8 No. of Employees: 3666 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80378 No. of Facilities: 405 (estimated) No. of Industries: 2 No. of Occupations: 6 No. of Employees: 4036 (estimated) No. of Female Employees: 2022 (estimated)

Hazard Codes	Xi
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	EB2985000

Bismuth(III) salicylate basic

Bismuth oxide salicylate

Bismuth Subsalicylate

4H-1,3,2-Benzodioxabismin-4-one, 2-hydroxy-

EINECS 238-953-1

MFCD00085368

Bismuth(III) subsalicylate

Bismuth, (2-hydroxybenzoato-O1,O2)oxo-

2-Hydroxy-4H-1,3,2-benzodioxabismin-4-one

Bismuth oxysalicylate

Pepto-Bismol

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Bismuth Subsalicylate
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Bismuth Subsalicylate
Price: ￥408.0/500g ￥128.0/100g
Purity: 97.0%
Delivery: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Bismuth oxide salicylate
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: Bismuth oxide salicylate
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Bismuth subsalicylate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: BISMUTH SUBSALICYLATE
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Get all suppliers and price by the below link:

Bismuth Subsalicylate suppliers

Price: $60/5g

Reference only. check more Bismuth Subsalicylate price

Bismuth Subsalicylate

Use of Bismuth Subsalicylate

Names