Prasugrel

Suppliers

Names

[ Name ]:
Prasugrel

[Synonym ]:
5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate
Prasugrel
Ethanone, 2-[2-(acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)-
Unii-34K66tbt99
Effient
Efient

Chemical & Physical Properties

[ Density]:
1.347

[ Boiling Point ]:
493.5ºC at 760 mmHg

[ Melting Point ]:
122 °C

[ Molecular Formula ]:
C₂₀H₂₀FNO₃S

[ Molecular Weight ]:
373.44100

[ Flash Point ]:
252.3ºC

[ Exact Mass ]:
373.11500

[ PSA ]:
74.85000

[ LogP ]:
3.82890

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.619

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

5-(2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one
Ethanone, 1-cyclopropyl-2-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-2-(2-fluorophenyl)
Ethanoic anhydride
Acetyl chloride
2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone
4,5,6,7-TETRAHYDROTHIENO[3,2-C]PYRIDIN-2(3H)-ONE HYDROCHLORIDE
5,6,7,7a-Tetrahydrothieno[3,2-c]pyridin-2(4H)-one 4-methylbenzenesulfonate
5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-3,4,6,7-tetrahydrothieno[3,2-c]pyridin-2-one
3-cyclopropyl-1-(2-fluorophenyl)-3-oxopropyl methanesulfonate

DownStream

Articles

Human valacyclovir hydrolase/biphenyl hydrolase-like protein is a highly efficient homocysteine thiolactonase.

PLoS ONE 9(10) , e110054, (2014)

Homocysteinylation of lysine residues by homocysteine thiolactone (HCTL), a reactive homocysteine metabolite, results in protein aggregation and malfunction, and is a well-known risk factor for cardio...

Effect of grapefruit juice on the bioactivation of prasugrel.

Br. J. Clin. Pharmacol. 80 , 139-45, (2015)

The P2Y12 inhibitor prasugrel is a prodrug, which is activated after its initial hydrolysis partly by cytochrome P450 (CYP) 3A4. Grapefruit juice, a strong inactivator of intestinal CYP3A4, greatly re...

Safety of short-term dual antiplatelet therapy after drug-eluting stents: An updated meta-analysis with direct and adjusted indirect comparison of randomized control trials.

Int. J. Cardiol. 181 , 331-9, (2015)

Duration of dual antiplatelet therapy (DAPT) following drug-eluting stents (DES) remains controversial and is a topic of ongoing research.Direct and adjusted indirect comparisons of all the recent ran...

Prasugrel-d5
Prasugrel-d4
Prasugrel-d3
prasugrel maleate
Prasugrel Impurity 3
Prasugrel Impurity 9
[(4-Fluoro-3-methylphenyl)methyl](methyl)amine hydrochloride
1-(Isoquinolin-5-yl)piperazin-2-one dihydrochloride
[(2R,3S)-2-(1-methyl-1H-pyrazol-5-yl)oxolan-3-yl]methanamine dihydrochloride
2-methyl-1-(pyrrolidin-3-yl)-4,5,6,7-tetrahydro-1H-1,3-benzodiazole dihydrochloride
5-Bromo-3-ethyl-1,2,3,4-tetrahydroisoquinoline hydrochloride
[(2-Bromo-5-fluorophenyl)methyl](methyl)amine hydrochloride
2H,3H-imidazo[2,1-b][1,3]thiazol-6-ylmethanamine hydrochloride
(2R,3S)-2-(pyridin-4-yl)oxan-3-amine dihydrochloride
4-[3-(Trifluoromethoxy)phenyl]oxan-4-amine hydrochloride
Methyl 3-hydroxypyridine-4-carboxylate hydrochloride

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