Prasugrel

Suppliers

Names

[ Name ]:
Prasugrel

[Synonym ]:
5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate
Prasugrel
Ethanone, 2-[2-(acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)-
Unii-34K66tbt99
Effient
Efient

Chemical & Physical Properties

[ Density]:
1.347

[ Boiling Point ]:
493.5ºC at 760 mmHg

[ Melting Point ]:
122 °C

[ Molecular Formula ]:
C₂₀H₂₀FNO₃S

[ Molecular Weight ]:
373.44100

[ Flash Point ]:
252.3ºC

[ Exact Mass ]:
373.11500

[ PSA ]:
74.85000

[ LogP ]:
3.82890

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.619

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

5-(2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one
Ethanone, 1-cyclopropyl-2-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-2-(2-fluorophenyl)
Ethanoic anhydride
Acetyl chloride
2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone
4,5,6,7-TETRAHYDROTHIENO[3,2-C]PYRIDIN-2(3H)-ONE HYDROCHLORIDE
5,6,7,7a-Tetrahydrothieno[3,2-c]pyridin-2(4H)-one 4-methylbenzenesulfonate
5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-3,4,6,7-tetrahydrothieno[3,2-c]pyridin-2-one
3-cyclopropyl-1-(2-fluorophenyl)-3-oxopropyl methanesulfonate

DownStream

Articles

Human valacyclovir hydrolase/biphenyl hydrolase-like protein is a highly efficient homocysteine thiolactonase.

PLoS ONE 9(10) , e110054, (2014)

Homocysteinylation of lysine residues by homocysteine thiolactone (HCTL), a reactive homocysteine metabolite, results in protein aggregation and malfunction, and is a well-known risk factor for cardio...

Effect of grapefruit juice on the bioactivation of prasugrel.

Br. J. Clin. Pharmacol. 80 , 139-45, (2015)

The P2Y12 inhibitor prasugrel is a prodrug, which is activated after its initial hydrolysis partly by cytochrome P450 (CYP) 3A4. Grapefruit juice, a strong inactivator of intestinal CYP3A4, greatly re...

Safety of short-term dual antiplatelet therapy after drug-eluting stents: An updated meta-analysis with direct and adjusted indirect comparison of randomized control trials.

Int. J. Cardiol. 181 , 331-9, (2015)

Duration of dual antiplatelet therapy (DAPT) following drug-eluting stents (DES) remains controversial and is a topic of ongoing research.Direct and adjusted indirect comparisons of all the recent ran...

Prasugrel-d5
Prasugrel-d4
Prasugrel-d3
prasugrel maleate
Prasugrel Impurity 3
Prasugrel Impurity 9
2-ethoxy-N-ethyl-N-[[4-(methylaminomethyl)phenyl]methyl]ethanamine
5-bromo-2-hydroxy-4-propoxy-benzaldehyde
N-[6-(1-naphthalenyl)-4-pyrimidinyl]-5-isoquinolinamine
1-(Cyclopropylmethyl)-1H-pyrazole-3-carbaldehyde
4-(Difluoromethoxy)naphthalen-1-amine
2-(Trimethylsilylethynyl)phenyl isocyanate
3-(3-Bromophenoxy)-1-methyl-1,2-dihydropyrazin-2-one
(3I(2),6I+/-,12I(2),23E)-25-Hydroperoxy-3,6,12-trihydroxydammar-23-en-20-yl I(2)-D-glucopyranoside
3-(2-Bromophenoxy)-1-methyl-1,2-dihydropyrazin-2-one
Cyclohexane, 2-ethoxy-1,3-dimethyl-

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