AB-MECA

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Names

[ CAS No. ]:
152918-26-8

[ Name ]:
AB-MECA

[Synonym ]:
N6-(4-Aminobenzyl)-N-methylcarboxamidoadenosine
[3H]AB-MECA
AB-MECA

Chemical & Physical Properties

[ Density]:
1.68g/cm3

[ Molecular Formula ]:
C18H21N7O4

[ Molecular Weight ]:
399.40400

[ Exact Mass ]:
399.16600

[ PSA ]:
163.93000

[ LogP ]:
0.88030

[ Index of Refraction ]:
1.789

[ Storage condition ]:
2-8℃

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

125I-4-aminobenzyl-5'-N-methylcarboxamidoadenosine, a high affinity radioligand for the rat A3 adenosine receptor.

Mol. Pharmacol. 45 , 978-982, (1994)

The rat A3 adenosine receptor (AR) is a recently characterized AR subtype cloned from testis and brain cDNA libraries. N6-2-(4-Amino-3-[125I]iodophenyl)ethyladenosine, a high affinity A1AR agonist, ha...

A role for central A3-adenosine receptors. Mediation of behavioral depressant effects.

FEBS Lett. 336 , 57-60, (1993)

The behavioral effects of a selective A3 adenosine receptor agonist 3-IB-MECA (N6-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine) in mice and the localization of radioligand binding sites in mouse bra...

Structure-activity relationships of N6-benzyladenosine-5'-uronamides as A3-selective adenosine agonists.

J. Med. Chem. 37 , 636-646, (1994)

Adenosine analogues modified at the 5'-position as uronamides and/or as N6-benzyl derivatives were synthesized. These derivatives were examined for affinity in radioligand binding assays at the newly ...


More Articles


Related Compounds

  • I-AB-MECA
  • ab-5529
  • AB-729
  • Heptanoic acid,6-hydroxy-6-methyl-,decahydro-3,7-dihydroxy-11-(4-methoxyphenyl)-5,8-epoxy-5H-(1,5)dioxecino(3,2-b)pyrrol-6-yl ester
  • ab-bis(cyclopentadienyl)-c-(μ-chloro)-d-(μ-neohexylidene)-ef-diisobutylzirconium(IV)aluminium
  • AB-506
  • (3-((1,3,4-Thiadiazol-2-yl)amino)phenyl)boronic acid
  • 5-{[(Tert-butoxy)carbonyl]amino}-3-(trifluoromethyl)pentanoic acid
  • Ethyl 4-hydroxy-1-methyl-1,2,5,6-tetrahydro-3-pyridinecarboxylate hydrochloride
  • (2-Chloro-6-methoxy-4-(methoxymethyl)phenyl)boronic acid
  • 2-Chloro-4-(ethylsulfanyl)pyridine
  • 1,5-Dibromo-3-ethyl-2-iodobenzene
  • N-(4',5-Dichloro[1,1'-biphenyl]-2-yl)-4-methoxybenzenesulfonamide
  • Benzyl-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-cyclohex-3-enyl]-carbamic acid tert-butyl ester
  • allyl (2S,4S)-2-(aminomethyl)-4-sulfanyl-pyrrolidine-1-carboxylate
  • 1,5-Diethoxy-2-fluoro-4-nitrobenzene
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