Clibucaine
Names
[ CAS No. ]:
15302-10-0
[ Name ]:
Clibucaine
[Synonym ]:
Clibucaina
3-Piperidino-buttersaeure-(2,4-dichlor-anilid)
Clibucaine
Clibucaina [INN-Spanish]
3-piperidino-butyric acid-(2,4-dichloro-anilide)
Clibucainum [INN-Latin]
Chemical & Physical Properties
[ Density]:
1.255g/cm3
[ Boiling Point ]:
466.8ºC at 760mmHg
[ Molecular Formula ]:
C15H20Cl2N2O
[ Molecular Weight ]:
315.24
[ Flash Point ]:
236.1ºC
[ Exact Mass ]:
314.09500
[ PSA ]:
35.83000
[ LogP ]:
4.78380
[ Vapour Pressure ]:
6.86E-09mmHg at 25°C
[ Index of Refraction ]:
1.585
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TN3712310
- CHEMICAL NAME :
- 1-Piperidinepropionanilide, 2',4'-dichloro-beta-methyl-
- CAS REGISTRY NUMBER :
- 15302-10-0
- BEILSTEIN REFERENCE NO. :
- 0249881
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C15-H20-Cl2-N2-O
- MOLECULAR WEIGHT :
- 315.27
- WISWESSER LINE NOTATION :
- T6NTJ AY1&1VMR BG DG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 150 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- HCACAV Helvetica Chimica Acta. (Verlag Helvetica Chimica Acta, Postfach, CH-4002 Basel, Switzerland) V.1- 1918- Volume(issue)/page/year: 38,1085,1955
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 220 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- HCACAV Helvetica Chimica Acta. (Verlag Helvetica Chimica Acta, Postfach, CH-4002 Basel, Switzerland) V.1- 1918- Volume(issue)/page/year: 38,1085,1955
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 59 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- HCACAV Helvetica Chimica Acta. (Verlag Helvetica Chimica Acta, Postfach, CH-4002 Basel, Switzerland) V.1- 1918- Volume(issue)/page/year: 38,1085,1955
Safety Information
[ HS Code ]:
2933399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933399090
[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%