Cyclo(-D-Ser-Pro-D-Val-Leu-D-Trp)

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Names

[ CAS No. ]:
153982-38-8

[ Name ]:
Cyclo(-D-Ser-Pro-D-Val-Leu-D-Trp)

[Synonym ]:
cyclo(D-Ser-Pro-D-Val-Leu-D-Trp)
JKC 302
Cyclo(-D-Ser-Pro-D-Val-Leu-D-Trp)

Chemical & Physical Properties

[ Molecular Formula ]:
C30H42N6O6

[ Molecular Weight ]:
582.69100

[ Exact Mass ]:
582.31700

[ PSA ]:
172.73000

[ LogP ]:
1.60170

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Cardiac myocytes control release of endothelin-1 in coronary vasculature.

Am. J. Physiol. Heart Circ. Physiol. 288 , H2088-2092, (2005)

Alpha-adrenergic vasoconstriction in the coronary circulation is mediated through alpha-adrenoceptors on cardiac myocytes and subsequent release of endothelin, a very potent, long-lasting vasoconstric...

The hemodynamic effects of endothelin receptor antagonism during a venous air infusion in dogs.

Anesth. Analg. 90 , 102-106, (2000)

Endothelin (ET) is involved in the humoral component of the vasoconstriction during pulmonary embolism. We examined the effects of selective ET receptor antagonists on the hemodynamic and respiratory ...

Location of alkali metal binding sites in endothelin A selective receptor antagonists, cyclo(D-Trp-D-Asp-Pro-D-Val-Leu) and cyclo(D-Trp-D-Asp-Pro-D-Ile-Leu), from multistep collisionally activated decompositions.

J. Mass Spectrom. 35 , 265-276, (2000)

We previously showed by using mass spectrometry that endothelin A selective receptor antagonists BQ123 and JKC301 form novel coordination compounds with sodium ions. This property may underlie the abi...


More Articles

Related Compounds

  • cyclo(sulfoalanyl-prolyl-valyl-leucyl-tryptophyl)
  • JKC-301
  • BE-18257B
  • Maculosin
  • Cyclo(D-Val-L-Pro)
  • Cyclo(-D-Trp-Tyr)