Cyclo(-D-Ser-Pro-D-Val-Leu-D-Trp)

Cyclo(-D-Ser-Pro-D-Val-Leu-D-Trp) Structure
Cyclo(-D-Ser-Pro-D-Val-Leu-D-Trp) structure
Common Name Cyclo(-D-Ser-Pro-D-Val-Leu-D-Trp)
CAS Number 153982-38-8 Molecular Weight 582.69100
Density N/A Boiling Point N/A
Molecular Formula C30H42N6O6 Melting Point N/A
MSDS Chinese USA Flash Point N/A

Cardiac myocytes control release of endothelin-1 in coronary vasculature.

Am. J. Physiol. Heart Circ. Physiol. 288 , H2088-2092, (2005)

Alpha-adrenergic vasoconstriction in the coronary circulation is mediated through alpha-adrenoceptors on cardiac myocytes and subsequent release of endothelin, a very potent, long-lasting vasoconstrictor. Recent studies found that adult cardiac myocytes do no...

The hemodynamic effects of endothelin receptor antagonism during a venous air infusion in dogs.

Anesth. Analg. 90 , 102-106, (2000)

Endothelin (ET) is involved in the humoral component of the vasoconstriction during pulmonary embolism. We examined the effects of selective ET receptor antagonists on the hemodynamic and respiratory changes and on serum thromboxane B2 (TXB2) levels, during a...

Location of alkali metal binding sites in endothelin A selective receptor antagonists, cyclo(D-Trp-D-Asp-Pro-D-Val-Leu) and cyclo(D-Trp-D-Asp-Pro-D-Ile-Leu), from multistep collisionally activated decompositions.

J. Mass Spectrom. 35 , 265-276, (2000)

We previously showed by using mass spectrometry that endothelin A selective receptor antagonists BQ123 and JKC301 form novel coordination compounds with sodium ions. This property may underlie the ability of an ET(A) antagonist to induce net tubular sodium re...