Chlortoluron

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Names

[ CAS No. ]:
15545-48-9

[ Name ]:
Chlortoluron

[Synonym ]:
Chlorotoluron
Methanol, 1-[(3-chloro-4-methylphenyl)imino]-1-(dimethylamino)-, (E)-
Urea, N'-(3-chloro-4-methylphenyl)-N,N-dimethyl-
N’-(3-chloro-4-methylphenyl)-N,N-dimethylurea
3-(3-Chloro-4-methylphenyl)-1,1-dimethylurea
MFCD00018275
Chlortoluron
3-(3-chloro-p-tolyl)-1,1-dimethylurea
EINECS 239-592-2
3-(3-Chloro-4-methyl)-1,1-dimethylurea
N'-(3-Chloro-4-methylphenyl)-N,N-dimethylcarbamimidic acid

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
345.9±52.0 °C at 760 mmHg

[ Melting Point ]:
147-148ºC

[ Molecular Formula ]:
C10H13ClN2O

[ Molecular Weight ]:
212.676

[ Flash Point ]:
163.0±30.7 °C

[ Exact Mass ]:
212.071640

[ PSA ]:
32.34000

[ LogP ]:
2.62

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.541

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YS7230000
CHEMICAL NAME :
Urea, 3-(3-chloro-p-tolyl)-1,1-dimethyl-
CAS REGISTRY NUMBER :
15545-48-9
BEILSTEIN REFERENCE NO. :
2647688
LAST UPDATED :
199701
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C10-H13-Cl-N2-O
MOLECULAR WEIGHT :
212.70
WISWESSER LINE NOTATION :
GR B1 EMVN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1300 mg/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
21 gm/kg/90D-C
TOXIC EFFECTS :
Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
2 gm/kg
SEX/DURATION :
female 4 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
10 mg/kg
SEX/DURATION :
male 50 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 58,353,1978

Safety Information

[ Symbol ]:

GHS08, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H351-H361d-H410

[ Precautionary Statements ]:
P273-P281-P501

[ Hazard Codes ]:
Xn:Harmful;N:Dangerousfortheenvironment;

[ Risk Phrases ]:
R40;R50/53;R63

[ Safety Phrases ]:
S26-S36/37-S46-S60-S61-S16

[ RIDADR ]:
UN 3077

[ RTECS ]:
YS7230000

[ HS Code ]:
2924299035

Synthetic Route

Precursor & DownStream

Precursor

  • 3-Chloro-4-methylphenyl isocyanate
  • Dimethylamine

DownStream

  • methylamine
  • Urea,(3-chloro-4-methylphenyl)-
  • Urea,N-(3-chloro-4-methylphenyl)-N'-methyl-
  • N'-(3-chloro-4-hydroxymethylphenyl)-N-methylurea
  • N'-(3-chloro-4-hydroxymethylphenyl)-N,N-dimethylurea
  • 2-Chloro-4-[(dimethylcarbamoyl)amino]benzoic acid
  • Dimethylamine
  • 2-Chloro-4-aminotoluene
  • dimethylcarbamic acid
  • 3-Chloro-4-methylphenyl isocyanate

Customs

[ HS Code ]: 2924299035

[ Summary ]:
2924299035 2-chlorobenzaldehyde。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%

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