3-Phenyl-1H-pyrazol-5-amine
Suppliers
Names
[ CAS No. ]:
1572-10-7
        
[ Name ]:
 3-Phenyl-1H-pyrazol-5-amine
        
[Synonym ]:
                
                MFCD00191749
                
                
            
                
                1H-Pyrazol-3-amine, 5-phenyl-
                
                
            
                
                1H-Pyrazol-5-amine, 3-phenyl-
                
                
            
                
                3-Phenyl-1H-pyrazol-5-amine
                
                
            
                
                3-Amino-5-phenylpyrazole
                
                
                
                
    
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
            
[ Boiling Point ]:
442.3±33.0 °C at 760 mmHg
            
[ Melting Point ]:
118-121ºC
            
[ Molecular Formula ]:
C9H9N3
            
[ Molecular Weight ]:
159.19
            
[ Flash Point ]:
251.5±12.6 °C
            
[ Exact Mass ]:
159.079651
            
[ PSA ]:
54.70000
            
[ LogP ]:
1.34
            
[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C
            
[ Index of Refraction ]:
1.663
            
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UQ6109000
- CHEMICAL NAME :
- Pyrazole, 5-amino-3-phenyl-
- CAS REGISTRY NUMBER :
- 1572-10-7
- BEILSTEIN REFERENCE NO. :
- 0004947
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C9-H9-N3
- MOLECULAR WEIGHT :
- 159.21
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 630 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 27,295,1964
Safety Information
[ Symbol ]:
                
                
                GHS07
            
[ Signal Word ]: 
Warning
            
[ Hazard Statements ]:
 H315-H319-H335
            
[ Precautionary Statements ]:
 P261-P305 + P351 + P338
            
[ Personal Protective Equipment ]:
 dust mask type N95 (US);Eyeshields;Gloves
            
[ Hazard Codes ]:
 Xi:Irritant;
            
[ Risk Phrases ]:
 R36/37/38
            
[ Safety Phrases ]:
 S26-S37/39
            
[ RIDADR ]: 
NONH for all modes of transport
            
[ WGK Germany ]: 
3
            
[ RTECS ]: 
UQ6109000
            
Precursor & DownStream
Precursor
DownStream
Articles
ChemMedChem 7(8) , 1453-64, (2012)
A library of new anthranilamide-pyrazolo[1,5-a]pyrimidine conjugates were designed, synthesized, and evaluated for their anticancer activity in cervical cancer cells such as HeLa and SiHa that possess...
Bioorg. Med. Chem. 17(8) , 3072-9, (2009)
Botulinum neurotoxin elicits its paralytic activity through a zinc-dependant metalloprotease that cleaves proteins involved in neurotransmitter release. Currently, no drugs are available to reverse th...
Org. Lett. 11(22) , 5214-7, (2009)
A mild one-step synthetic method to access privileged heterobiaryl pyrazolo[3,4-b]pyridines from indole-3-carboxaldehyde derivatives and a variety of aminopyrazoles has been developed. This novel meth...