3-Phenyl-1H-pyrazol-5-amine

3-Phenyl-1H-pyrazol-5-amine Structure
3-Phenyl-1H-pyrazol-5-amine structure
Common Name 3-Phenyl-1H-pyrazol-5-amine
CAS Number 1572-10-7 Molecular Weight 159.19
Density 1.2±0.1 g/cm3 Boiling Point 442.3±33.0 °C at 760 mmHg
Molecular Formula C9H9N3 Melting Point 118-121ºC
MSDS Chinese USA Flash Point 251.5±12.6 °C
Symbol GHS07
GHS07
Signal Word Warning

Anthranilamide-pyrazolo[1,5-a]pyrimidine conjugates as p53 activators in cervical cancer cells.

ChemMedChem 7(8) , 1453-64, (2012)

A library of new anthranilamide-pyrazolo[1,5-a]pyrimidine conjugates were designed, synthesized, and evaluated for their anticancer activity in cervical cancer cells such as HeLa and SiHa that possess low levels of p53. All 24 conjugates showed antiproliferat...

Botulinum neurotoxin serotype A inhibitors: small-molecule mercaptoacetamide analogs.

Bioorg. Med. Chem. 17(8) , 3072-9, (2009)

Botulinum neurotoxin elicits its paralytic activity through a zinc-dependant metalloprotease that cleaves proteins involved in neurotransmitter release. Currently, no drugs are available to reverse the effects of botulinum intoxication. Herein we report the d...

An efficient one-step synthesis of heterobiaryl pyrazolo[3,4-b]pyridines via indole ring opening.

Org. Lett. 11(22) , 5214-7, (2009)

A mild one-step synthetic method to access privileged heterobiaryl pyrazolo[3,4-b]pyridines from indole-3-carboxaldehyde derivatives and a variety of aminopyrazoles has been developed. This novel method constructs heterobiaryls with the wide scope of substrat...

The conversion of isothiazoles into pyrazoles using hydrazine. Ioannidou HA and Koutentis PA

Tetrahedron 65(34) , 7023-7037, (2009)

Crystal structure of chlorido-tris (3-amino-5-phenyl-1H pyrazole-N2) zinc (II) chloride, [ZnCl (C9H9N3)3] Cl. Jacimovic ZK, et al

Zeitsch. für Kristall. 226(3) , 397-399, (2011)

Convenient synthesis of some new pyrazolo [5, 1-c] triazines, isoxazolo [3, 4-d] pyrimidine and pyridine derivatives containing benzofuran moiety. Abdelhamid AO, et al

Eur. J. Chem. 3(2) , 129-137, (2012)

Syntheses of 3-pyrimidyl-and 3-pyranyl-5, 6-benzocoumarin derivatives. El-Deen IM, et al

Bull. Korean Chem. Soc. 23(4) , 610-612, (2002)

Recent advances in the chemistry of ethoxycarbonyl isothiocyanate and related compounds. George B and Papadopoulos EP

J. Heterocycl. Chem. 20(5) , 1127-1142, (1983)