GDP-L-fucose disodium salt

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Names

[ CAS No. ]:
15839-70-0

[ Name ]:
GDP-L-fucose disodium salt

[Synonym ]:
[(2R,3S,4R,5R)-5-(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydro-2-furanyl]methyl (3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl dihydrogen diphosphate (non-preferred name)
GDP-β-L-FUCOSE, DISODIUM SALT
Guanosine 5'-diphospho-β-L-fucose disodium salt
Guanosine diphosphate fucose
GDP-L-fucose disodium salt

Chemical & Physical Properties

[ Density]:
2.4±0.1 g/cm3

[ Boiling Point ]:
1006.6ºC at 760 mmHg

[ Molecular Formula ]:
C16H23N5Na2O15P2

[ Molecular Weight ]:
589.342

[ Flash Point ]:
562.6ºC

[ Exact Mass ]:
589.082214

[ PSA ]:
336.77000

[ LogP ]:
-2.95

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.869

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Precursor & DownStream

Precursor

  • GDP-4-dehydro-6-deoxy-α-D-mannose
  • 2,3,4-tri-O-benzoylfucopyranosyl bromide
  • 1,2,3,4-Tetra-O-benzoyl-L-fucopyranose
  • ACETOBROMOFUCOSE
  • dibenzylphosphoryl 2,3,4-tri-O-acetyl-L-fucoside

DownStream

  • GDP
  • 6-O-A-L-FUCOPYRANOSYL-N,N'-*DIACETYLCHIT OBIOSE

Articles

Low glucose depletes glycan precursors, reduces site occupancy and galactosylation of a monoclonal antibody in CHO cell culture.

Biotechnol. J. 10 , 1051-66, (2015)

Controlled feeding of glucose has been employed previously to enhance the productivity of recombinant glycoproteins but there is a concern that low concentrations of glucose could limit the synthesis ...

Chemo-enzymatic supported synthesis of the 3-sulfated Lewis a pentasaccharide on a multimeric polyethylene glycol.

Carbohydr. Res. 343(5) , 970-6, (2008)

The 3-sulfated Lewis(a) pentasaccharide was synthesized on multimeric-based polyethylene glycol support. Coupling of O-(2,3,4,6-tetra-O-acetyl-beta-D-galactopyranosyl)-(1-->3)-4,6-di-O-acetyl-2-deoxy-...

Structures of NodZ α1,6-fucosyltransferase in complex with GDP and GDP-fucose.

Acta Crystallogr. D Biol. Crystallogr. 68 , 160-168, (2012)

Rhizobial NodZ α1,6-fucosyltransferase (α1,6-FucT) catalyzes the transfer of the fucose (Fuc) moiety from guanosine 5'-diphosphate-β-L-fucose to the reducing end of the chitin oligosaccharide core dur...


More Articles


Related Compounds

  • GDP-BETA-L-FUCOSE BIS(TRIETHYLAMMONIUM) SALT
  • GDP-ALPHA-D-MANNOSE, DISODIUM SALT
  • GDP-L-Fuc.2Na
  • ALPHA-L-(-)-FUCOSE 1-PHOSPHATE DI(CYLOHEXYLAMMONIUM) SALT
  • L-()-Malic acid disodium salt
  • l(-)-malic acid disodium salt monohydrate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 4-Ethyloxazolidine-2-imine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 3-(chloromethyl)-N-ethylbenzamide
  • N-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1,3,4,9-tetrahydro-2H-beta-carboline-2-carboxamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde