GDP-L-fucose disodium salt

Modify Date: 2024-01-23 16:31:14

GDP-L-fucose disodium salt Structure
GDP-L-fucose disodium salt structure
Common Name GDP-L-fucose disodium salt
CAS Number 15839-70-0 Molecular Weight 589.342
Density 2.4±0.1 g/cm3 Boiling Point 1006.6ºC at 760 mmHg
Molecular Formula C16H23N5Na2O15P2 Melting Point N/A
MSDS USA Flash Point 562.6ºC

 Use of GDP-L-fucose disodium salt


GDP-L-fucose is a nucleotide sugar that is a key substrate for the biosynthesis of fucose oligosaccharides, providing the fucose moiety for the oligosaccharides.The formation of GDP-L-fucose occurs through two pathways, the major ab initio metabolic pathway and the minor remedial metabolic pathway[1].

 Names

Name Guanosine 5′-diphospho-β-L-fucose sodium salt
Synonym More Synonyms

 GDP-L-fucose disodium salt Biological Activity

Description GDP-L-fucose is a nucleotide sugar that is a key substrate for the biosynthesis of fucose oligosaccharides, providing the fucose moiety for the oligosaccharides.The formation of GDP-L-fucose occurs through two pathways, the major ab initio metabolic pathway and the minor remedial metabolic pathway[1].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Weiyang Wang, et al. Cell-free enzymatic synthesis of GDP-L-fucose from mannose. AMB Express. 2019 May 27;9(1):74.  

 Chemical & Physical Properties

Density 2.4±0.1 g/cm3
Boiling Point 1006.6ºC at 760 mmHg
Molecular Formula C16H23N5Na2O15P2
Molecular Weight 589.342
Flash Point 562.6ºC
Exact Mass 589.082214
PSA 336.77000
LogP -2.95
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.869

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Articles31

More Articles
Low glucose depletes glycan precursors, reduces site occupancy and galactosylation of a monoclonal antibody in CHO cell culture.

Biotechnol. J. 10 , 1051-66, (2015)

Controlled feeding of glucose has been employed previously to enhance the productivity of recombinant glycoproteins but there is a concern that low concentrations of glucose could limit the synthesis ...

Chemo-enzymatic supported synthesis of the 3-sulfated Lewis a pentasaccharide on a multimeric polyethylene glycol.

Carbohydr. Res. 343(5) , 970-6, (2008)

The 3-sulfated Lewis(a) pentasaccharide was synthesized on multimeric-based polyethylene glycol support. Coupling of O-(2,3,4,6-tetra-O-acetyl-beta-D-galactopyranosyl)-(1-->3)-4,6-di-O-acetyl-2-deoxy-...

Structures of NodZ α1,6-fucosyltransferase in complex with GDP and GDP-fucose.

Acta Crystallogr. D Biol. Crystallogr. 68 , 160-168, (2012)

Rhizobial NodZ α1,6-fucosyltransferase (α1,6-FucT) catalyzes the transfer of the fucose (Fuc) moiety from guanosine 5'-diphosphate-β-L-fucose to the reducing end of the chitin oligosaccharide core dur...

 Synonyms

[(2R,3S,4R,5R)-5-(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydro-2-furanyl]methyl (3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl dihydrogen diphosphate (non-preferred name)
GDP-β-L-FUCOSE, DISODIUM SALT
Guanosine 5'-diphospho-β-L-fucose disodium salt
Guanosine diphosphate fucose
GDP-L-fucose disodium salt
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