Zoledronic acid hydrate

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Names

[ CAS No. ]:
165800-06-6

[ Name ]:
Zoledronic acid hydrate

[Synonym ]:
(1-hydroxy-2-imidazol-1-yl-1-phosphonoethyl)phosphonic acid,hydrate
Zoledronic acid monohydrate
Reclast
Zometa
[1-Hydroxy-2-(1H-imidazol-1-yl)-1,1-ethanediyl]bis(phosphonic acid) hydrate (1:1)
Phosphonic acid, [1-hydroxy-2-(1H-imidazol-1-yl)ethylidene]bis-, hydrate (1:1)
(1-Hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl)diphosphonic acid hydrate
MFCD08448695
Aclasta
1-Hydroxy-2-(1-imidazolyl)ethane-1,1-diphosphonic Acid Monohydrate
[1-Hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl]bis(phosphonic acid) hydrate (1:1)
Zoledronic acid hydrate
Zoledronic acid
Zoledronic acid (monohydrate)

Chemical & Physical Properties

[ Boiling Point ]:
764ºC at 760 mmHg

[ Melting Point ]:
245 °C(dec.)

[ Molecular Formula ]:
C5H12N2O8P2

[ Molecular Weight ]:
290.105

[ Flash Point ]:
415.8ºC

[ Exact Mass ]:
290.006897

[ PSA ]:
181.96000

[ Vapour Pressure ]:
1.53E-24mmHg at 25°C

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P305 + P351 + P338

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933290090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Zoledronic acid

DownStream

Customs

[ HS Code ]: 2933290090

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

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J. Cancer Res. Clin. Oncol. 142 , 611-8, (2016)

Mevalonate pathway inhibitors are potentially useful chemotherapeutic agents showing growth inhibition and pro-apoptotic effects in cancer cells. The effects of statins and bisphosphonates on cancer g...


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Related Compounds

  • Zoledronic Acid-¹⁵N2,¹³C2
  • Zoledronic Acid Related Compound
  • Zoledronic Acid Related Compound
  • Zoledronic acid impurity A
  • Zoledronic Acid, Disodium Salt, Tetrahydrate
  • Zoledronic acid
  • 4-(1-Methyl-1H-pyrazol-5-yl)butan-1-ol
  • 4-Cyano-2,5-difluorobenzenesulfonamide
  • 4-(1-methyl-1H-pyrazol-5-yl)butanal
  • 4-(2-Methylimidazo[1,2-b]pyridazin-3-yl)-N-phenyl-2-pyrimidinamine
  • 5-(4-Chlorobutyl)-1-methyl-1H-pyrazole
  • 3-(5-Bromo-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenol
  • 5-Bromo-2-[4-(phenylmethoxy)phenyl]-1H-pyrrolo[2,3-b]pyridine
  • n-(4-Bromo-benzyl)-4-pentyl-n-piperidin-4-yl-benzamide
  • 4-(4-Nitro-phenyl)-morpholine-3-carboxylic acid methyl ester
  • 3-(4-Cyanophenyl)-2-hydroxypropanoic acid
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