Zoledronic acid hydrate
Modify Date: 2025-08-24 20:50:32
Zoledronic acid hydrate structure
|
Common Name | Zoledronic acid hydrate | ||
|---|---|---|---|---|
| CAS Number | 165800-06-6 | Molecular Weight | 290.105 | |
| Density | N/A | Boiling Point | 764ºC at 760 mmHg | |
| Molecular Formula | C5H12N2O8P2 | Melting Point | 245 °C(dec.) | |
| MSDS | Chinese USA | Flash Point | 415.8ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of Zoledronic acid hydrateZoledronic acid monohydrate is a third-generation, nitrogen-containing bisphosphonate, inhibits osteoclast-mediated bone resorption, and also has antitumor activity. |
| Name | Zoledronic acid hydrate |
|---|---|
| Synonym | More Synonyms |
| Description | Zoledronic acid monohydrate is a third-generation, nitrogen-containing bisphosphonate, inhibits osteoclast-mediated bone resorption, and also has antitumor activity. |
|---|---|
| Related Catalog | |
| In Vitro | Zoledronic acid monohydrate induces apoptosis in HGF and HaCaT cells at 0.5 μM, and causes cell death at 1-5 μM[1]. Zoledronic Acid (50, 100 μM) causes dose- and time-dependent apoptosis in CNE-2Z cells after treatment for 24, 48, and 72 h. Zoledronic Acid (50 μM) also increases the level of ROS, which is supposed to mediate Cl- currents activation in CNE-2Z cells. Furthermore, the apoptosis and chloride currents induced by Zoledronic Acid can be blocked by knocking down ClC-3 protein expression[2]. |
| References |
| Boiling Point | 764ºC at 760 mmHg |
|---|---|
| Melting Point | 245 °C(dec.) |
| Molecular Formula | C5H12N2O8P2 |
| Molecular Weight | 290.105 |
| Flash Point | 415.8ºC |
| Exact Mass | 290.006897 |
| PSA | 181.96000 |
| Vapour Pressure | 1.53E-24mmHg at 25°C |
| Storage condition | 2-8°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2933290090 |
|
~88%
Zoledronic acid... CAS#:165800-06-6 |
| Literature: GADOR S.A. Patent: WO2007/16982 A1, 2007 ; Location in patent: Page/Page column 7-8 ; |
| Precursor 1 | |
|---|---|
| DownStream 0 | |
| HS Code | 2933290090 |
|---|---|
| Summary | 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
|
Caveolae as a target to quench autoinduction of the metastatic phenotype in lung cancer.
J. Cancer Res. Clin. Oncol. 142 , 611-8, (2016) Mevalonate pathway inhibitors are potentially useful chemotherapeutic agents showing growth inhibition and pro-apoptotic effects in cancer cells. The effects of statins and bisphosphonates on cancer g... |
| (1-hydroxy-2-imidazol-1-yl-1-phosphonoethyl)phosphonic acid,hydrate |
| Zoledronic acid monohydrate |
| Reclast |
| Zometa |
| [1-Hydroxy-2-(1H-imidazol-1-yl)-1,1-ethanediyl]bis(phosphonic acid) hydrate (1:1) |
| Phosphonic acid, [1-hydroxy-2-(1H-imidazol-1-yl)ethylidene]bis-, hydrate (1:1) |
| (1-Hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl)diphosphonic acid hydrate |
| MFCD08448695 |
| Aclasta |
| 1-Hydroxy-2-(1-imidazolyl)ethane-1,1-diphosphonic Acid Monohydrate |
| [1-Hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl]bis(phosphonic acid) hydrate (1:1) |
| Zoledronic acid hydrate |
| Zoledronic acid |
| Zoledronic acid (monohydrate) |
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- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Zoledronic acid hydrate
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- China
- Product Name: Zoledronic acid hydrate
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- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: Zoledronic acid hydrate
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- DC Chemicals Limited
- China
- Product Name: Zoledronic acid hydrate
- Price: $300.0/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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- China
- Product Name: Zoledronic acid injection
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
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Price: ￥79/250mg
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