4-hydroxyantipyrine

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Names

[ CAS No. ]:
1672-63-5

[ Name ]:
4-hydroxyantipyrine

[Synonym ]:
MFCD00003143
1-phenyl-2,3-dimethyl-4-hydroxy-pyrazoline-5-on
4-hydroxy-1,5-dimethyl-2-phenyl-1,2-dihydro-3h-pyrazol-3-one
4-Hydroxy-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one
1-Phenyl-2,3-dimethyl-4-hydroxy-5-pyrazolone
Prestwick_270
hydroxy-4 antipyrine
1,2-dihydro-4-hydroxy-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one
Antipyrine,4-hydroxy
4-Hydroxyantipyrine

Chemical & Physical Properties

[ Density]:
1.294g/cm3

[ Boiling Point ]:
314.3ºC at 760mmHg

[ Melting Point ]:
184-186ºC(lit.)

[ Molecular Formula ]:
C11H12N2O2

[ Molecular Weight ]:
204.22500

[ Flash Point ]:
143.9ºC

[ Exact Mass ]:
204.09000

[ PSA ]:
47.16000

[ LogP ]:
1.19000

[ Vapour Pressure ]:
0.000199mmHg at 25°C

[ Index of Refraction ]:
1.63

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Precursor & DownStream

Precursor

  • 3H-Pyrazol-3-one,4-bromo-1,2-dihydro-1,5-dimethyl-2-phenyl-
  • Antipyrine
  • aminophenazone
  • 4-Aminoantipyrine
  • propyphenazone

DownStream

  • N,N'-Diphenylethanediamide
  • N-Methyl-N-phenyl oxamide
  • 2-(C,N-dimethylcarbonimidoyl)-6-methyl-4-oxo-N-phenylhepta-2,5-dienamide
  • (1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl) hydrogen sulfate
  • N-methyl-N-phenyl-acetohydrazide
  • Bernsteinsaeure[bis(1,1'-methyl-2,2'-phenyl)hydrazid-(1,1')]
  • Oxalic acid

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

The effect of age and sex on metabolism and urinary excretion of antipyrine.

J. Gerontol. A. Biol. Sci. Med. Sci. 53(1) , M14-9, (1998)

Drug-metabolizing capacity is generally reduced in the elderly. The purpose of this investigation was to study antipyrine clearance and metabolite excretion in old subjects of both sexes.Saliva cleara...

The pharmacokinetics of antipyrine and three of its metabolites in the rabbit: intravenous administration of pure metabolites.

Pharm. Res. 8(12) , 1470-6, (1991)

Antipyrine (AP) is a commonly used probe of oxidative metabolism. Indirect evidence demonstrates formation rate limited disposition of its metabolites. Kinetic studies using antipyrine and its major m...

Separation and identification of the 4-hydroxyantipyrine sulphoconjugate.

J. Chromatogr. A. 576(1) , 103-9, (1992)

In a previous study we observed, during separation of total antipyrine metabolites by high-performance liquid chromatography and after enzymatic hydrolysis, an unidentified peak corresponding to an io...


More Articles


Related Compounds

  • 4-Hydroxyantipyrine-d3
  • 4-Hydroxyantipyrine Sulfate
  • 4-Amino-2-chloro-5-(1H-tetrazol-5-yl)benzenesulfonamide
  • 4-(4-Chlorophenyl)-4-Bromopiperide
  • 4-(2-nitroimidazol-1-yl)butane-1,2-diol
  • 4-Iodo-1H-indazole-3-carboxylic acid
  • N-[(3-Bromothiophen-2-yl)methyl]-4-methylpyridin-3-amine
  • [(1-ethyl-1H-pyrazol-5-yl)methyl](3-methoxypropyl)amine
  • [(1-Ethyl-1H-pyrazol-5-yl)methyl](oxolan-2-ylmethyl)amine
  • 2-{[(2-Bromo-4-methylphenyl)methyl]amino}propane-1,3-diol
  • N-[(1-Ethyl-1H-pyrazol-5-yl)methyl]pyridin-3-amine
  • 2,6-dimethyl-N-propyloxan-4-amine
  • 2,6-Dimethyl-N-(3-methylbutyl)oxan-4-amine
  • US9580449, Example A253
  • 2,6-Dimethyl-N-(oxolan-2-ylmethyl)oxan-4-amine
  • 2,6-Dimethyl-N-(thiophen-2-ylmethyl)oxan-4-amine
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