N-Cbz-L-serine methyl ester

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Names

[ CAS No. ]:
1676-81-9

[ Name ]:
N-Cbz-L-serine methyl ester

[Synonym ]:
L-Serine, N-[(phenylmethoxy)carbonyl]-, methyl ester
Methyl N-[(benzyloxy)carbonyl]-L-serinate
N-Carbobenzyloxy-L-serine methyl ester
N-Carbobenzoxy-L-serine Methyl Ester
CBZ-L-Serine methyl ester
N-Cbz-L-serine Methyl Ester
N-Benzyloxycarbonyl-l-serine, methyl ester
MFCD00077039
Cbz-Ser-OMe
(S)-Methyl 2-(((benzyloxy)carbonyl)amino)-3-hydroxypropanoate
methyl (2S)-3-hydroxy-2-(phenylmethoxycarbonylamino)propanoate
Z-Ser-OMe

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
442.6±45.0 °C at 760 mmHg

[ Melting Point ]:
41-43 °C(lit.)

[ Molecular Formula ]:
C12H15NO5

[ Molecular Weight ]:
253.251

[ Flash Point ]:
221.5±28.7 °C

[ Exact Mass ]:
253.095016

[ PSA ]:
84.86000

[ LogP ]:
1.42

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.536

[ Storage condition ]:
-15°C

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • H-Ser-Ome·HCl
  • Benzyl chloroformate
  • N-Cbz-L-Serine
  • methyl iodide
  • Methanol
  • l-serine methyl ester
  • diazomethane
  • Dimethyl sulfate
  • benzyl triazolo[4,5-b]pyridine-1-carboxylate

DownStream

  • Cbz-beta-Amino-L-alanine
  • (S)-methyl 3-amino-2-(((benzyloxy)carbonyl)amino)propanoate hydrochloride
  • (S)-BENZYL (3-HYDROXY-1-(METHYLAMINO)-1-OXOPROPAN-2-YL)CARBAMATE
  • Diphenyl phosphate
  • L-Serine,N-[(phenylmethoxy)carbonyl]-O-[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-b-D-glucopyranosyl]-, methyl ester
  • o-tert-butyl-n-carbobenzoxy-l-serine methyl ester
  • N-Cbz-L-Serine
  • N-Benzyloxycarbonylserylleucinamide
  • Z-Ser-Gly-OH

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Stereoselective Synthesis of Differentially Protected Derivatives of the Higher Amino Sugars Destomic Acid and Lincosamine from Serine and Threonine.

J. Org. Chem. 61 , 581, (1996)

The aminoheptose destomic acid (3.5) and the aminooctose lincosamine (6.8) were synthesized in protected form by parallel sequences starting from the oxazolidine derivatives 2.4 and 5.1 of N-CBz serin...

Monache, G.D. et al.

Synthesis , 1155, (1995)

Demirci, F. et al.

Synthesis , 189, (1996)


More Articles

Related Compounds

  • O-tert-Butyl-N-Cbz-L-serine Methyl Ester
  • Methyl N-[(benzyloxy)carbonyl]-D-serinate
  • N-benzylidene-L-serine methyl ester
  • N-ACETYL-L-SERINE METHYL ESTER
  • N-benzyl-L-serine methyl ester hydrochloride
  • N-(benzoyl)-L-serine methyl ester
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • 1-[(2-Ethoxy-4,5-dimethylphenyl)sulfonyl]-4-methylpiperazine
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide