N-Benzyloxycarbonyl-L-proline tert-butyl ester

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Names

[ CAS No. ]:
16881-39-3

[ Name ]:
N-Benzyloxycarbonyl-L-proline tert-butyl ester

[Synonym ]:
N-Benzyloxycarbonyl-L-proline tert-butyl ester
1-Benzyl 2-tert-butyl (2S)-pyrrolidine-1,2-dicarboxylate
N-Carbobenzoxy-L-proline tert-Butyl Ester
1,2-Pyrrolidinedicarboxylic acid, 2-(1,1-dimethylethyl) 1-(phenylmethyl) ester, (2S)-
EINECS 240-911-2
1-Benzyl 2-(2-methyl-2-propanyl) (2S)-1,2-pyrrolidinedicarboxylate
N-CBZ-L-PROLINE TERT-BUTYL ESTER
MFCD00051777

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
404.8±45.0 °C at 760 mmHg

[ Melting Point ]:
45ºC

[ Molecular Formula ]:
C17H23NO4

[ Molecular Weight ]:
305.369

[ Flash Point ]:
198.6±28.7 °C

[ Exact Mass ]:
305.162720

[ PSA ]:
55.84000

[ LogP ]:
2.87

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.533

[ Storage condition ]:
-15°C

MSDS

Click to get detail MSDS

Safety Information

[ Safety Phrases ]:
S22-S24/25

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Z-Pro-OH
  • tert-Butanol
  • Di-tert-butyl dicarbonate
  • Oxalyl chloride
  • Isobutylene
  • tert-butyl (2S)-2-{[(benzyloxy)carbonyl]amino}-5-bromo pentanoate
  • 2-Bromo-2-methylpropane
  • 1,1-Di-tert-butoxy-N,N-dimethylmethanamine
  • tert-Butyl acetate

DownStream

  • H-Pro-OtBu
  • Z-Pro-OH

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • N-(N-benzyloxycarbonyl-L-alanyl)-L-proline tert-butyl ester
  • (2S,4S)-4-hydroxy-1-phenylmethoxycarbonylpyrrolidine-2-carboxylic acid tert-butyl ester
  • (2S,4R)-4-hydroxy-1-phenylmethoxycarbonylpyrrolidine-2-carboxylic acid tert-butyl ester
  • N-[(Phenylmethoxy)carbonyl]-L-valyl-L-proline tert-butyl ester
  • N-benzyl-L-proline tert-butyl ester
  • N-benzyloxycarbonyl-L-seryl-L-tyrosine tert-butyl ester
  • Furan-3-yl(3-(pyrazin-2-yloxy)piperidin-1-yl)methanone
  • 2-(2-Fluorophenyl)-1-(3-(pyrazin-2-yloxy)piperidin-1-yl)ethanone
  • 1-(3-(pyrazin-2-yloxy)piperidin-1-yl)-2-(1H-pyrrol-1-yl)ethanone
  • N-(2-oxo-2-(3-(pyrazin-2-yloxy)piperidin-1-yl)ethyl)acetamide
  • 2-Hydroxy-2-phenyl-1-(3-(pyrazin-2-yloxy)piperidin-1-yl)ethanone
  • 2-(Benzo[d][1,3]dioxol-5-yl)-1-(3-(pyrazin-2-yloxy)piperidin-1-yl)ethanone
  • Indolizin-2-yl(3-(pyrazin-2-yloxy)piperidin-1-yl)methanone
  • (2-Hydroxyquinolin-4-yl)(3-(pyrazin-2-yloxy)piperidin-1-yl)methanone
  • (3-(Pyrazin-2-yloxy)piperidin-1-yl)(6-(trifluoromethyl)pyridin-3-yl)methanone
  • (5-Chloro-6-hydroxypyridin-3-yl)(3-(pyrazin-2-yloxy)piperidin-1-yl)methanone
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