Spiro[2,5-cyclohexadiene-1,7'(1'H)-cyclopent[ij]isoquinolin]-4-one,2',3',8',8'a-tetrahydro-6'-hydroxy-5'-methoxy-1'-methyl-

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Names

[ CAS No. ]:
17127-48-9

[ Name ]:
Spiro[2,5-cyclohexadiene-1,7'(1'H)-cyclopent[ij]isoquinolin]-4-one,2',3',8',8'a-tetrahydro-6'-hydroxy-5'-methoxy-1'-methyl-

[Synonym ]:
Unii-ke7J8A65p6
Glaziovina [inn-spanish]
N-Methyl-crotsparin
(+-)-Glaziovin
Glaziovinum
Glaziovina
Glaziovinum [inn-latin]
N-methylcrotsparine

Chemical & Physical Properties

[ Density]:
1.33g/cm3

[ Boiling Point ]:
470.8ºC at 760mmHg

[ Molecular Formula ]:
C18H19NO3

[ Molecular Weight ]:
297.34800

[ Flash Point ]:
238.5ºC

[ Exact Mass ]:
297.13600

[ PSA ]:
49.77000

[ LogP ]:
2.20430

[ Vapour Pressure ]:
1.74E-09mmHg at 25°C

[ Index of Refraction ]:
1.668

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-Methylcoclaurine

DownStream

Related Compounds

  • 4-[[8-Methoxy-6-(5-thiazolyl)-4-quinazolinyl]amino]benzamide
  • 4-[[6-(5-Thiazolyl)-8-(trifluoromethyl)-4-quinazolinyl]amino]benzamide
  • 4-[(3-Chloro-4-fluorophenyl)amino]-8-methyl-6-(5-thiazolyl)-2(1h)-quinazolinone
  • N-(3-chloro-4-fluorophenyl)-6-(5-thiazolyl)-4-quinolinamine
  • N-phenyl-6-(5-thiazolyl)-4-quinazolinamine
  • N-(4-fluorophenyl)-6-(5-thiazolyl)-4-quinazolinamine
  • N-(3-fluorophenyl)-6-(5-thiazolyl)-4-quinazolinamine
  • N-(2-fluorophenyl)-6-(5-thiazolyl)-4-quinazolinamine
  • N-[4-[[6-(5-thiazolyl)-4-quinazolinyl]amino]phenyl]methanesulfonamide
  • N-[3-(methylsulfonyl)phenyl]-6-(5-thiazolyl)-4-quinazolinamine