α-tocotrienol

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Names

[ Name ]:
α-tocotrienol

[Synonym ]:
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-2H-1-benzopyran-6-ol
alpha-tocotrienol
D-α-Tocotrienol
2,5,7,8-Tetramethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatri en-1-yl]-6-chromanol

Chemical & Physical Properties

[ Density]:
0.96g/cm3

[ Boiling Point ]:
541.7ºC at 760mmHg

[ Molecular Formula ]:
C₂₉H₄₄O₂

[ Molecular Weight ]:
424.65800

[ Flash Point ]:
222.3ºC

[ Exact Mass ]:
424.33400

[ PSA ]:
29.46000

[ LogP ]:
8.60050

[ Vapour Pressure ]:
2.39E-12mmHg at 25°C

[ Index of Refraction ]:
1.522

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

Tocotrienols promote apoptosis in human breast cancer cells by inducing poly(ADP-ribose) polymerase cleavage and inhibiting nuclear factor kappa-B activity.

Cell Prolif. 46(2) , 203-13, (2013)

Tocotrienols and tocopherols are members of the vitamin E family, with similar structures; however, only tocotrienols have been reported to achieve potent anti-cancer effects. The study described here...

Tissue distribution of vitamin E metabolites in rats after oral administration of tocopherol or tocotrienol.

J. Nutr. Sci. Vitaminol. 57(5) , 326-32, (2011)

We previously found that 2,7,8-trimethyl-2(2'-carboxyethyl)-6-hydroxychroman (_CEHC), a metabolite of the vitamin E isoforms _-tocopherol or _-tocotrienol, accumulated in the rat small intestine. The ...

δ- and γ-tocotrienols induce classical ultrastructural apoptotic changes in human T lymphoblastic leukemic cells.

Microsc. Microanal. 18(3) , 462-9, (2012)

Tocotrienols are isomers of the vitamin E family, which have been reported to exert cytotoxic effects in various cancer cells. Although there have been some reports on the effects of tocotrienols in l...

α-Tocotrienol
α-tocotrienol
α-Tocotrienol
α-tocotrienol acetate
(2S,4'R,8'R)-2',5',11'-α-tocotrienol benzyl ether
α-(3,4-Dimethoxyphenyl)-4-[(3,4-dimethoxyphenyl)methyl]tetrahydro-3-hydroxyfuran-3-methanol
4-(5-Bromo-2-methoxypyridin-3-yl)-1,3-oxazolidin-2-one
2-[1-(2,2-difluoroethyl)-5-(oxolan-3-yl)-1H-1,2,3-triazol-4-yl]acetonitrile
tert-butyl N-methyl-N-[2-(3-nitrophenyl)-1-oxopropan-2-yl]carbamate
Benzyl 5-hydroxy-5-(trifluoromethyl)-2-azabicyclo[2.2.1]heptane-2-carboxylate
tert-butyl N-(5-amino-2,3-dimethoxyphenyl)carbamate
1-[(2,3-Dihydro-1-benzofuran-5-yl)methyl]-2,2-dimethylcyclopropan-1-amine
1-Amino-3-(5-nitropyridin-2-yl)propan-2-ol
(3-Chloro-2,6-difluorophenyl)methanesulfonyl fluoride
1-(1-Methylpiperidin-4-yl)prop-2-en-1-one
tert-butyl N-{2-[(azetidin-3-yl)methyl]-4-methoxyphenyl}carbamate

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