chloropyrimidine

Suppliers

Names

[ CAS No. ]:
1722-12-9

[ Name ]:
chloropyrimidine

[Synonym ]:
2-Chloro-4-deoxyuracil
2-Chloro-pyrimindine
EINECS 217-020-2
chloro-pyrimidine
2-Chloropyrimindine
MFCD00006060
chloropyrimidine
2-pyrimidyl chloride
2-Chloropyrimidine
2-Cl-pyrimidine
Pyrimidine, 2-chloro-
2CPY X HCL
2-Chloro
pyrimidin-2-yl chloride
2-chloro-pyrimidine
2-chloro-pyrimidin
2-choropyrimidine
PYRIMIDINE,2-CHLORO
2-pyrimidinyl chloride
2-chloropyrimide

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
199.2±0.0 °C at 760 mmHg

[ Melting Point ]:
63-66 °C(lit.)

[ Molecular Formula ]:
C4H3ClN2

[ Molecular Weight ]:
114.533

[ Flash Point ]:
109.2±4.3 °C

[ Exact Mass ]:
113.998474

[ PSA ]:
25.78000

[ LogP ]:
0.36

[ Vapour Pressure ]:
0.5±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.535

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H319

[ Precautionary Statements ]:
P301 + P312 + P330-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
2811

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Amino-4,6-dichloropyrimidine
  • 4-Methoxyphenylethylamine
  • 2-(4-Methoxyphenyl)ethanol
  • 4-(2-Chloroethyl)anisole
  • 2-Chloro-5-pyrimidineboronic acid
  • 2-Aminopyrimidine
  • pyrimidone
  • 2,4-Dichloropyrimidine
  • Triethylaluminum

DownStream

  • Methyl 5-methyl-2-(pyrimidin-2-yl)benzoate
  • 2-Pyrimidinamine, N-3-butynyl- (9CI)
  • Methyl 4-(pyrimidin-2-yloxy)benzoate
  • bipyrimidine
  • 2-Chloro-4-(methylsulfanyl)pyrimidine
  • 2-(4-Methylpiperazin-1-yl)pyrimidine
  • 2-Pyrimidinamine, N-cyclobutyl- (9CI)
  • 2-PYRIMIDINAMINE, N,N-DIMETHYL-
  • N-cyclohexyl-N-methylpyrimidin-2-amine
  • 2-Pyrimidinamine, N-cyclopropyl- (9CI)

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Cobalt-catalyzed cross-coupling between in situ prepared arylzinc halides and 2-chloropyrimidine or 2-chloropyrazine.

J. Org. Chem. 74(8) , 3221-4, (2009)

A cobalt-catalyzed cross-coupling of aryl halides with 2-chloropyrimidines or 2-chloropyrazines is reported in satisfactory to high yields. The key step of this procedure is the formation of aromatic ...

Ru-catalysed C-H arylation of indoles and pyrroles with boronic acids: scope and mechanistic studies.

Chemistry 21(14) , 5380-6, (2015)

The Ru-catalysed C2-H arylation of indoles and pyrroles by using boronic acids under oxidative conditions is reported. This reaction can be applied to tryptophan derivatives and tolerates a wide range...

Expedient parallel synthesis of 2-amino-4-heteroarylpyrimidines.

Org. Lett. 7(19) , 4113-6, (2005)

[reaction: see text] An expedient synthesis of diverse 2-amino-4-heteroarylpyrimidines via a 2-chloropyrimidine intermediate is described. A series of potentially biologically active analogues have be...


More Articles

Related Compounds

  • 4-Chloropyrimidine
  • dichloropyrimidine
  • 5-Chloropyrimidine
  • 4-CHLOROPYRIMIDINE HCL
  • 4-Chloropyrimidine 2HCl
  • 4-Amino-2-chloropyrimidine
  • 2-Pyridinamine, 4-methyl-5-(2,4,6-trimethoxyphenyl)-
  • Methyl 3-(4-fluoro-3-methoxyphenyl)benzoate
  • 5-Hydroxy-N,N-dimethyl-2-(trifluoromethyl)benzamide
  • 2-[3-Methyl-5-(tetrazol-1-yl)pyridin-2-yl]acetic acid
  • 5-methyl-2-piperazin-1-yl-1H-benzimidazole dihydrochloride
  • 2-Formyl-5-hydroxy-N,N-dimethylbenzamide
  • 4-formyl-3,4-dihydro-1H-isochromene-8-carbonitrile
  • 8,8-dimethyl-5-phenyl-4a,5,5a,7,9,9a,10,10a-octahydro-1H-pyrimido[4,5-b]quinoline-2,4,6-trione
  • n-[5-(4-Methanesulfonyl-phenyl)-4-methyl-thiazol-2-yl]-acetamide
  • 7-Hydroxy-3-(4-hydroxyphenoxy)-4a,5,6,7,8,8a-hexahydrochromen-4-one
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