PB 28 dihydrochloride

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Names

[ CAS No. ]:
172906-90-0

[ Name ]:
PB 28 dihydrochloride

[Synonym ]:
1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine,dihydrochloride

Chemical & Physical Properties

[ Molecular Formula ]:
C24H38N2O

[ Molecular Weight ]:
443.49300

[ Exact Mass ]:
442.25200

[ PSA ]:
15.71000

[ LogP ]:
6.32540

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-Cyclohexylpiperazine
  • (3-bromopropyl)tetralin
  • 4-(3-bromo-n-propyl)-1,2-dihydro-8-methoxynaphthalene

DownStream

Articles

A new method for evaluating sigma(2) ligand activity in the isolated guinea-pig bladder.

Naunyn Schmiedebergs Arch. Pharmacol. 368 , 106-112, (2003)

We demonstrated the presence of sigma(2) receptors in the guinea-pig ileum by saturation analysis and extended our investigation to guinea-pig bladder and rat bladder. In functional assays of the isol...


More Articles

Related Compounds

  • PB 28 dihydrochloride
  • PB 28 dihydrochloride
  • [Pb(2,6-(2,4,6-(isopropyl)3C6H2)2C6H3)N(methyl)2]2
  • PB-cadherin
  • Pb(OC(O)Ph)4
  • Pb(NMe2)2
  • 3-[(6-Bromo-2-cyclobutylquinazolin-4-yl)sulfanyl]propanoic acid
  • 3-[(6-Chloro-2-methylquinazolin-4-yl)sulfanyl]propanoic acid
  • 2-[5-(cyclopropylmethyl)-1-pentyl-1H-1,2,3-triazol-4-yl]acetonitrile
  • 3-[(6-Chloro-2-ethylquinazolin-4-yl)sulfanyl]propanoic acid
  • 3-{[6-Chloro-2-(ethoxymethyl)quinazolin-4-yl]sulfanyl}propanoic acid
  • 1-ethyl-5-(oxiran-2-yl)-1H-1,2,4-triazole
  • 3-Hydroxy-3-(4-methylthiophen-2-yl)propanenitrile
  • 3-{[2-Methyl-6-(trifluoromethyl)quinazolin-4-yl]sulfanyl}propanoic acid
  • 3-{[2-Cyclobutyl-6-(trifluoromethyl)quinazolin-4-yl]sulfanyl}propanoic acid
  • 3-{[7-Bromo-2-(methoxymethyl)quinazolin-4-yl]sulfanyl}propanoic acid
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