PB 28 dihydrochloride

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Names

[ CAS No. ]:
172906-90-0

[ Name ]:
PB 28 dihydrochloride

[Synonym ]:
1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine,dihydrochloride

Chemical & Physical Properties

[ Molecular Formula ]:
C24H38N2O

[ Molecular Weight ]:
443.49300

[ Exact Mass ]:
442.25200

[ PSA ]:
15.71000

[ LogP ]:
6.32540

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-Cyclohexylpiperazine
  • (3-bromopropyl)tetralin
  • 4-(3-bromo-n-propyl)-1,2-dihydro-8-methoxynaphthalene

DownStream

Articles

A new method for evaluating sigma(2) ligand activity in the isolated guinea-pig bladder.

Naunyn Schmiedebergs Arch. Pharmacol. 368 , 106-112, (2003)

We demonstrated the presence of sigma(2) receptors in the guinea-pig ileum by saturation analysis and extended our investigation to guinea-pig bladder and rat bladder. In functional assays of the isol...


More Articles

Related Compounds

  • PB 28 dihydrochloride
  • PB 28 dihydrochloride
  • [Pb(2,6-(2,4,6-(isopropyl)3C6H2)2C6H3)N(methyl)2]2
  • PB-cadherin
  • Pb(OC(O)Ph)4
  • Pb(NMe2)2
  • N-{1-[3-(dimethylamino)propyl]-2-methyl-1H-benzimidazol-5-yl}-2-(1-methyl-1H-indol-3-yl)acetamide
  • 2-(1-(1H-pyrrol-1-yl)cyclohexyl)-N-(5-cyclopropyl-1,3,4-thiadiazol-2-yl)acetamide
  • N-[1-(4-fluorobenzyl)-4-piperidyl]-3-(2-pyrimidinylamino)benzamide
  • 2-(3-isobutyl-4-oxo-3,4-dihydrophthalazin-1-yl)-N-(thiazol-2-yl)acetamide
  • N-{1-[3-(dimethylamino)propyl]-1H-benzimidazol-5-yl}-3-(1H-indol-3-yl)propanamide
  • 2-{[4-(4-fluorophenyl)piperazin-1-yl]methyl}-3-hydroxy-1-methyl-6-(morpholin-4-ylmethyl)pyridin-4(1H)-one
  • 2-(3,5-dimethyl-1,2-oxazol-4-yl)-N-(3-{1-[4-(2-methylpropyl)phenyl]ethyl}-1H-1,2,4-triazol-5-yl)acetamide
  • 3-(4-methoxyphenyl)-1-methyl-N-[3-([1,2,4]triazolo[4,3-a]pyridin-3-yl)propyl]-1H-pyrazole-5-carboxamide
  • 3-(1,3-dioxo-1,3-dihydro-2H-pyrrolo[3,4-c]pyridin-2-yl)-N-(4H-1,2,4-triazol-3-yl)propanamide
  • 1-(4,6-dimethylpyrimidin-2-yl)-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]piperidine-3-carboxamide
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