(5S)-5-(Hydroxymethyl)pyrrolidin-2-on

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Names

[ CAS No. ]:
17342-08-4

[ Name ]:
(5S)-5-(Hydroxymethyl)pyrrolidin-2-on

[Synonym ]:
MFCD00077792
T5MVTJ E1Q &&(S)-(+)- Form
(5S)-(+)-5-(Hydroxymethyl)-2-pyrrolidinone
2-Pyrrolidinone, 5-(hydroxymethyl)-, (5S)-
2-Pyrrolidinone, 5-(hydroxymethyl)-, (5S)-(+)-
(S)-5-(Hydroxymethyl)-2-pyrrolidinone
(S)-(+)-5-(Hydroxymethyl)-2-pyrrolidinone
(5S)-5-(Hydroxymethyl)pyrrolidin-2-on
(S)-(+)-5-Hydroxymethyl-2-pyrrolidinone
(5S)-(+)-5-(Hydroxymethyl)pyrrolidin-2-one
(5S)-5-(Hydroxymethyl)-2-pyrrolidinone
(5S)-5-(hydroxymethyl)pyrrolidin-2-one

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
346.0±15.0 °C at 760 mmHg

[ Melting Point ]:
79-80 °C(lit.)

[ Molecular Formula ]:
C5H9NO2

[ Molecular Weight ]:
115.131

[ Flash Point ]:
163.0±20.4 °C

[ Exact Mass ]:
115.063332

[ PSA ]:
49.33000

[ LogP ]:
-2.49

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.476

[ Storage condition ]:
2~8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933790090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Methyl L-Pyroglutamate
  • H-Pyr-OEt
  • L-Pyroglutamicacid
  • Dimethyl Glutamate
  • L-(+)Sodium glutamate
  • L-glutamic acid
  • H-Glu(OEt)-OEt.HCl

DownStream

  • (5S)-5-[[[(tert-Butyl)dimethylsilyl]oxy]methyl]-2-pyrrolidinone
  • (5S)-5-(azidomethyl)pyrrolidin-2-one
  • (S)-(+)-5-(Hydroxymethyl)-2-pyrrolidinone p-toluenesulfonate
  • swainsonine
  • Boc-L-Pyroglutaminol
  • (5S)-5-(Brommethyl)pyrrolidin-2-on
  • (R)-1-(CHLOROMETHYL)-5-METHYL-2-PYRROLIDINONE
  • trans-4-Cyclohexyl-L-proline
  • (3R,7AS)-3-PHENYLTETRAHYDROPYRROLO[1,2-C]OXAZOL-5(3H)-ONE
  • (S)-5-(tert-butoxycarbonyl)-5-azaspiro[2.4]heptane-6-carboxylic acid

Customs

[ HS Code ]: 2933790090

[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

Articles

J. Org. Chem. 57 , 2158, (1992)

Tetrahedron 48 , 2143, (1992)


More Articles

Related Compounds

  • (5S)-5-(Hydroxymethyl)pyrrolidin-2-on
  • (5S)-5-(Brommethyl)pyrrolidin-2-on
  • (5S)-5-(hydroxymethyl)-3,3-dimethylpyrrolidin-2-one
  • (5S)-5-[bis(4-fluorophenyl)-hydroxymethyl]pyrrolidin-2-one
  • (5S)-(5-hydroxymethyl-2-oxo-2,5-dihydrofuran-3-yl)carbamic acid benzyl ester
  • tert-Butyl ((3R,5S)-5-(hydroxyMethyl)pyrrolidin-3-yl)carbamate
  • N-[4-(1,4,5,6-Tetrahydro-6-oxo-3-pyridazinyl)phenyl]thiourea
  • 7-Methoxy-1-methyl-3,1-benzoxazine-2,4-dione
  • Methyl [(2-pyridin-4-yl[1,2,4]triazolo[1,5-c]quinazolin-5-yl)thio]acetate
  • 1-(3,4-Dimethoxyphenyl)-2-{[2-(pyridin-4-yl)[1,2,4]triazolo[1,5-c]quinazolin-5-yl]sulfanyl}ethanone
  • 4-amino-5-[3-(4-methylphenyl)-1H-pyrazol-5-yl]-4H-1,2,4-triazole-3-thiol
  • Methyl I+/--chloro-1,2,3-thiadiazole-4-acetate
  • S-Propyl 4-(chloromethyl)-1,2,3-thiadiazole-5-carbothioate
  • 4-[8-(3-Methylsulfanyl-phenyl)-[1,7]naphthyridin-6-yl]-cyclohexanecarboxylic acid
  • Piperazine,1-[[1-[(4-fluorophenyl)methyl]-1h-pyrrolo[2,3-b]pyridin-3-yl]oxoacetyl]-4-methyl-
  • 4-Chloro-6-(trifluoromethyl)quinoline-2(1H)-one
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