(5S)-5-(Hydroxymethyl)pyrrolidin-2-on

Modify Date: 2024-01-02 17:12:31

(5S)-5-(Hydroxymethyl)pyrrolidin-2-on Structure
(5S)-5-(Hydroxymethyl)pyrrolidin-2-on structure
Common Name (5S)-5-(Hydroxymethyl)pyrrolidin-2-on
CAS Number 17342-08-4 Molecular Weight 115.131
Density 1.2±0.1 g/cm3 Boiling Point 346.0±15.0 °C at 760 mmHg
Molecular Formula C5H9NO2 Melting Point 79-80 °C(lit.)
MSDS Chinese USA Flash Point 163.0±20.4 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name L-Pyroglutaminol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 346.0±15.0 °C at 760 mmHg
Melting Point 79-80 °C(lit.)
Molecular Formula C5H9NO2
Molecular Weight 115.131
Flash Point 163.0±20.4 °C
Exact Mass 115.063332
PSA 49.33000
LogP -2.49
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.476
Storage condition 2~8°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933790090

 Synthetic Route

~10%

(5S)-5-(Hydroxymethyl)pyrrolidin-2-on Structure

(5S)-5-(Hydroxy...

CAS#:17342-08-4

Literature: Zheng, Pinguan; Gondo, Chenaimwoyo A.; Bode, Jeffrey W. Chemistry - An Asian Journal, 2011 , vol. 6, # 2 p. 614 - 620

~88%

(5S)-5-(Hydroxymethyl)pyrrolidin-2-on Structure

(5S)-5-(Hydroxy...

CAS#:17342-08-4

Literature: Busque, Felix; De March, Pedro; Figueredo, Marta; Font, Josep; Gallagher, Timothy; Milan, Sergio Tetrahedron Asymmetry, 2002 , vol. 13, # 4 p. 437 - 445

~%

(5S)-5-(Hydroxymethyl)pyrrolidin-2-on Structure

(5S)-5-(Hydroxy...

CAS#:17342-08-4

Literature: US2004/225133 A1, ; Page 6-7 ;

~86%

(5S)-5-(Hydroxymethyl)pyrrolidin-2-on Structure

(5S)-5-(Hydroxy...

CAS#:17342-08-4

Literature: Smith III, Amos B.; Friestad, Gregory K.; Barbosa, Joseph; Bertounesque, Emmanuel; Duan, James J.-W.; Hull, Kenneth G.; Iwashima, Makoto; Qiu, Yuping; Spoors, P. Grant; Salvatore, Brian A. Journal of the American Chemical Society, 1999 , vol. 121, # 45 p. 10478 - 10486

~92%

(5S)-5-(Hydroxymethyl)pyrrolidin-2-on Structure

(5S)-5-(Hydroxy...

CAS#:17342-08-4

Literature: Studer, Martin; Burkhardt, Stefan; Blaser, Hans-Ulrich Advanced Synthesis and Catalysis, 2001 , vol. 343, # 8 p. 802 - 808

~%

(5S)-5-(Hydroxymethyl)pyrrolidin-2-on Structure

(5S)-5-(Hydroxy...

CAS#:17342-08-4

Literature: US2004/225133 A1, ; Page 6 ;

~%

(5S)-5-(Hydroxymethyl)pyrrolidin-2-on Structure

(5S)-5-(Hydroxy...

CAS#:17342-08-4

Literature: Tetrahedron Letters, , vol. 27, # 14 p. 1533 - 1536

~%

(5S)-5-(Hydroxymethyl)pyrrolidin-2-on Structure

(5S)-5-(Hydroxy...

CAS#:17342-08-4

Literature: Tetrahedron Letters, , vol. 27, # 3 p. 369 - 372

~%

(5S)-5-(Hydroxymethyl)pyrrolidin-2-on Structure

(5S)-5-(Hydroxy...

CAS#:17342-08-4

Literature: Synthetic Communications, , vol. 19, # 20 p. 3485 - 3496

 Customs

HS Code 2933790090
Summary 2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

 Articles2

More Articles

J. Org. Chem. 57 , 2158, (1992)

Tetrahedron 48 , 2143, (1992)

 Synonyms

MFCD00077792
T5MVTJ E1Q &&(S)-(+)- Form
(5S)-(+)-5-(Hydroxymethyl)-2-pyrrolidinone
2-Pyrrolidinone, 5-(hydroxymethyl)-, (5S)-
2-Pyrrolidinone, 5-(hydroxymethyl)-, (5S)-(+)-
(S)-5-(Hydroxymethyl)-2-pyrrolidinone
(S)-(+)-5-(Hydroxymethyl)-2-pyrrolidinone
(5S)-5-(Hydroxymethyl)pyrrolidin-2-on
(S)-(+)-5-Hydroxymethyl-2-pyrrolidinone
(5S)-(+)-5-(Hydroxymethyl)pyrrolidin-2-one
(5S)-5-(Hydroxymethyl)-2-pyrrolidinone
(5S)-5-(hydroxymethyl)pyrrolidin-2-one
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