7-hydroxy Warfarin

Suppliers

Names

[ CAS No. ]:
17834-03-6

[ Name ]:
7-hydroxy Warfarin

[Synonym ]:
7-Hydroxywarfarin
4,7-dihydroxy-3-(3-oxo-1-phenylbutyl)chromen-2-one

Chemical & Physical Properties

[ Density]:
1.384g/cm3

[ Boiling Point ]:
540.2ºC at 760mmHg

[ Melting Point ]:
220ºC

[ Molecular Formula ]:
C19H16O5

[ Molecular Weight ]:
324.33

[ Flash Point ]:
197.7ºC

[ Exact Mass ]:
324.10000

[ PSA ]:
87.74000

[ LogP ]:
3.31520

[ Vapour Pressure ]:
1.68E-12mmHg at 25°C

[ Index of Refraction ]:
1.658

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H318

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2932209090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Warfarin

DownStream

Customs

[ HS Code ]: 2932209090

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, S-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole.

Drug Metab. Dispos. 43 , 1408-16, (2015)

The common marmoset (Callithrix jacchus), a small New World monkey, has the potential for use in human drug development due to its evolutionary closeness to humans. Four novel cDNAs, encoding cytochro...

Investigation of two-dimensional high performance liquid chromatography approaches for reversed phase resolution of warfarin and hydroxywarfarin isomers.

J. Chromatogr. A. 1363 , 200-6, (2014)

Several offline and online 2D HPLC methods were investigated for the reversed phase resolution of a complex mixture of closely related warfarin and hydroxywarfarin isomers. By combining reversed phase...

Hydroxywarfarin metabolites potently inhibit CYP2C9 metabolism of S-warfarin.

Chem. Res. Toxicol. 23(5) , 939-45, (2010)

Coumadin (R/S-warfarin) anticoagulant therapy poses a risk to over 50 million Americans, in part due to interpersonal variation in drug metabolism. Consequently, it is important to understand how meta...


More Articles

Related Compounds

  • 7-HYDROXYWARFARIN
  • 7-Hydroxy Warfarin-d5
  • (R)-7-Hydroxy Warfarin
  • (7-BENZYL-7-AZABICYCLO[2.2.1]HEPTAN-1-YL)METHANAMINE
  • 7-Hydroxymethyl-3-oxa-bicyclo[3.3.1]nonan-9-one
  • 7-methylguanosine-5'-monophosphate
  • N-((4,6-dimethoxy-1,3,5-triazin-2-yl)methyl)-3,5-dimethylisoxazole-4-sulfonamide
  • N-[(4,6-dimethoxy-1,3,5-triazin-2-yl)methyl]quinoline-8-sulfonamide
  • 1-((4,6-Dimethoxy-1,3,5-triazin-2-yl)methyl)-3-(4-(trifluoromethoxy)phenyl)urea
  • 1-((4,6-Dimethoxy-1,3,5-triazin-2-yl)methyl)-3-(2,3,4-trifluorophenyl)urea
  • 1-((4,6-Dimethoxy-1,3,5-triazin-2-yl)methyl)-3-(3-(methylthio)phenyl)urea
  • 1-((4,6-Dimethoxy-1,3,5-triazin-2-yl)methyl)-3-(4-((trifluoromethyl)thio)phenyl)urea
  • N-[(4,6-dimethoxy-1,3,5-triazin-2-yl)methyl]-1-(3,4-dimethylphenyl)-5-oxopyrrolidine-3-carboxamide
  • 2-(2-chlorophenyl)-N-[(4,6-dimethoxy-1,3,5-triazin-2-yl)methyl]acetamide
  • N-[(4,6-dimethoxy-1,3,5-triazin-2-yl)methyl]thiophene-3-carboxamide
  • N-((4,6-dimethoxy-1,3,5-triazin-2-yl)methyl)-1-(thiophen-2-yl)cyclopentanecarboxamide