(3-Carboxypropyl)(triphenyl)phosphonium bromide

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Names

[ CAS No. ]:
17857-14-6

[ Name ]:
(3-Carboxypropyl)(triphenyl)phosphonium bromide

[Synonym ]:
(3-Carboxypropyl)triphenylphosphonium bromide
(3-Carboxypropyl)(triphenyl)phosphonium bromide
Ph3PCH2CH2CH2COOH bromide
Phosphonium, (3-carboxypropyl)triphenyl-, bromide (1:1)
(4-Hydroxy-4-oxobutyl)triphenylphosphonium bromide
MFCD00274196
3-Carboxypropyl triphenylphosphonium bromide

Chemical & Physical Properties

[ Melting Point ]:
244-247 °C(lit.)

[ Molecular Formula ]:
C22H22BrO2P

[ Molecular Weight ]:
429.287

[ Exact Mass ]:
428.054077

[ PSA ]:
50.89000

[ LogP ]:
0.84930

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Precursor & DownStream

Precursor

  • 4-Bromobutanoic acid
  • Triphenylphosphine
  • gamma-Butyrolactone
  • Triphenylphosphine hydrobromide (1:1)

DownStream

  • Phosphonium,(4-ethoxy-4-oxobutyl)triphenyl-, bromide (1:1)
  • 2-CHLORO-6,7,8,9-TETRAHYDRO-BENZOCYCLOHEPTEN-5-ONE
  • 2-Methoxy-6,7,8,9-tetrahydrobenzocyclohepten-5-one
  • 2-Bromo-6,7,8,9-tetrahydrobenzocyclohepten-5-one
  • (4E)-4-[(1R,4S,5R,6S)-5-[(3S)-3-cyclohexyl-3-hydroxyprop-1-ynyl]-4-hydroxy-8-bicyclo[4.2.0]octanylidene]butanoic acid
  • (E)-4-((1S,2S,3R,6S)-2-((S)-3-cyclohexyl-3-hydroxyprop-1-yn-1-yl)-3-hydroxybicyclo[4.2.0]octan-7-ylidene)butanoic acid
  • 5-(3-Methoxyphenyl)pentanoic acid
  • 5H-Benzocyclohepten-5-one,6,7,8,9-tetrahydro-2-methoxy-3-nitro-
  • 10-methoxy-11-nitro-bicyclo[5.4.0]undeca-8,10,12-trien-6-one
  • 5-(4-METHYLPHENYL)VALERIC ACID

Articles

Mitochondrial delivery of doxorubicin via triphenylphosphine modification for overcoming drug resistance in MDA-MB-435/DOX cells.

Mol. Pharm. 11(8) , 2640-9, (2014)

In this study, doxorubicin (DOX) was conjugated to a lipophilic triphenylphosphonium (TPP) that is selectively taken up by the mitochondrial membrane of cells. This new derivative of DOX, i.e., TPP-DO...


More Articles

Related Compounds

  • (3-Bromopropyl)(triphenyl)phosphonium bromide
  • 3-carboxypropyl(triphenyl)phosphanium,chloride
  • 3-carboxypropyl(triphenyl)phosphanium,nitrate
  • 3-carboxypropyl(triphenyl)phosphanium,iodide
  • 3,5-diacetoxybenzyl-(triphenyl)phosphonium bromide
  • (3,5-Bis-methoxycarbonyl-benzyl)-triphenyl-phosphonium; bromide
  • 5-fluoro-6-methyl-2-[5-(3,4,5-trimethoxybenzoyl)-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-2-yl]-5H-pyrimidin-4-one
  • 6-[4-[(2-Cyclopropylimidazo[1,2-b]pyridazin-6-yl)oxymethyl]piperidine-1-carbonyl]diazinan-3-one
  • N-[2-(2,4-dioxo-4aH-pyrido[2,3-d]pyrimidin-3-yl)ethyl]-1-benzothiophene-2-carboxamide
  • 6-Phenyl-5-[4-[(3-propan-2-yl-1,2,4-oxadiazol-5-yl)methyl]piperazin-1-yl]diazinan-3-one
  • 5-fluoro-6-propan-2-yl-2-[4-(quinoxaline-6-carbonyl)piperazin-1-yl]-5H-pyrimidin-4-one
  • [3-[(6-Phenylpyridazin-3-yl)oxymethyl]pyrrolidin-1-yl]-pyrazolidin-4-ylmethanone
  • 1-[1-(1-Methylcyclohexyl)cyclopropyl]ethan-1-amine
  • 2-[4-[[6-(3,5-dimethylpyrazol-1-yl)pyrimidin-4-yl]oxymethyl]piperidine-1-carbonyl]-2H-pyrazin-3-one
  • N-[[3-(2-oxopiperidin-4-yl)-1,2,4-oxadiazol-5-yl]methyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
  • 5-[4-(Azepan-1-ylsulfonyl)piperazin-1-yl]-6-phenyldiazinan-3-one
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