(3-Carboxypropyl)(triphenyl)phosphonium bromide

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Names

[ CAS No. ]:
17857-14-6

[ Name ]:
(3-Carboxypropyl)(triphenyl)phosphonium bromide

[Synonym ]:
(3-Carboxypropyl)triphenylphosphonium bromide
(3-Carboxypropyl)(triphenyl)phosphonium bromide
Ph3PCH2CH2CH2COOH bromide
Phosphonium, (3-carboxypropyl)triphenyl-, bromide (1:1)
(4-Hydroxy-4-oxobutyl)triphenylphosphonium bromide
MFCD00274196
3-Carboxypropyl triphenylphosphonium bromide

Chemical & Physical Properties

[ Melting Point ]:
244-247 °C(lit.)

[ Molecular Formula ]:
C22H22BrO2P

[ Molecular Weight ]:
429.287

[ Exact Mass ]:
428.054077

[ PSA ]:
50.89000

[ LogP ]:
0.84930

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Precursor & DownStream

Precursor

  • 4-Bromobutanoic acid
  • Triphenylphosphine
  • gamma-Butyrolactone
  • Triphenylphosphine hydrobromide (1:1)

DownStream

  • Phosphonium,(4-ethoxy-4-oxobutyl)triphenyl-, bromide (1:1)
  • 2-CHLORO-6,7,8,9-TETRAHYDRO-BENZOCYCLOHEPTEN-5-ONE
  • 2-Methoxy-6,7,8,9-tetrahydrobenzocyclohepten-5-one
  • 2-Bromo-6,7,8,9-tetrahydrobenzocyclohepten-5-one
  • (4E)-4-[(1R,4S,5R,6S)-5-[(3S)-3-cyclohexyl-3-hydroxyprop-1-ynyl]-4-hydroxy-8-bicyclo[4.2.0]octanylidene]butanoic acid
  • (E)-4-((1S,2S,3R,6S)-2-((S)-3-cyclohexyl-3-hydroxyprop-1-yn-1-yl)-3-hydroxybicyclo[4.2.0]octan-7-ylidene)butanoic acid
  • 5-(3-Methoxyphenyl)pentanoic acid
  • 5H-Benzocyclohepten-5-one,6,7,8,9-tetrahydro-2-methoxy-3-nitro-
  • 10-methoxy-11-nitro-bicyclo[5.4.0]undeca-8,10,12-trien-6-one
  • 5-(4-METHYLPHENYL)VALERIC ACID

Articles

Mitochondrial delivery of doxorubicin via triphenylphosphine modification for overcoming drug resistance in MDA-MB-435/DOX cells.

Mol. Pharm. 11(8) , 2640-9, (2014)

In this study, doxorubicin (DOX) was conjugated to a lipophilic triphenylphosphonium (TPP) that is selectively taken up by the mitochondrial membrane of cells. This new derivative of DOX, i.e., TPP-DO...


More Articles


Related Compounds

  • (3-Bromopropyl)(triphenyl)phosphonium bromide
  • 3-carboxypropyl(triphenyl)phosphanium,chloride
  • 3-carboxypropyl(triphenyl)phosphanium,nitrate
  • 3-carboxypropyl(triphenyl)phosphanium,iodide
  • 3,5-diacetoxybenzyl-(triphenyl)phosphonium bromide
  • (3,5-Bis-methoxycarbonyl-benzyl)-triphenyl-phosphonium; bromide
  • N-benzyl-1-{3-[(4-fluorophenyl)methyl]-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl}piperidine-4-carboxamide
  • 1-(3-chlorophenyl)-2-(methylthio)-5-phenyl-1H-imidazole
  • tert-Butyl ((3R,5R)-5-(hydroxymethyl)pyrrolidin-3-yl)carbamate hydrochloride
  • 2-Isopropylpiperazine dihydrochloride
  • 4-((2-((2-((2-chlorophenyl)amino)-2-oxoethyl)thio)-4-oxoquinazolin-3(4H)-yl)methyl)-N-cyclopropylbenzamide
  • (1S,4S)-tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate hydrochloride
  • N-cyclopropyl-4-((2-((2-((3,4-dimethylphenyl)amino)-2-oxoethyl)thio)-4-oxoquinazolin-3(4H)-yl)methyl)benzamide
  • N-cyclopropyl-4-((2-((2-((2-ethylphenyl)amino)-2-oxoethyl)thio)-4-oxoquinazolin-3(4H)-yl)methyl)benzamide
  • (R)-methyl 2-(piperidin-2-yl)acetate HCl
  • (5,9-Dihydro-6,8-dioxa-benzocyclohepten-7-ylmethyl)-furan-2-ylmethyl-amine hcl
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