formoterol fumarate dihydrate

Suppliers

Names

[ Name ]:
formoterol fumarate dihydrate

[Synonym ]:
formoterol fumerate dihydrate
Formamide, N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (2E)-2-butenedioate, hydrate (2:1:2) (salt)
Formoterol hemifumarate,(±)-(R,R)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamidehemifumarate
N-{2-Hydroxy-5-[(1R)-1-hydroxy-2-{[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino}ethyl]phenyl}formamide (2E)-but-2-enedioate hydrate (2:1:2)
Formoterol fumarate dihydrate
Formoterol fumarate
N-{2-Hydroxy-5-[(1R)-1-hydroxy-2-{[(2R)-1-(4-methoxyphenyl)-2-propanyl]amino}ethyl]phenyl}formamide (2E)-2-butenedioate hydrate (2:1:2)

Chemical & Physical Properties

[ Boiling Point ]:
603.2ºC at 760 mmHg

[ Melting Point ]:
116-120ºC

[ Molecular Formula ]:
C₄₂H₅₆N₄O₁₄

[ Molecular Weight ]:
840.912

[ Flash Point ]:
318.6ºC

[ Exact Mass ]:
840.379272

[ PSA ]:
274.70000

[ LogP ]:
6.22940

[ Vapour Pressure ]:
2.12E-15mmHg at 25°C

[ Storage condition ]:
Store at RT

[ Water Solubility ]:
DMSO: soluble20mg/mL

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
UN 2811 6.1 / PGII

[ HS Code ]:
2924299090

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Permeation of Therapeutic Drugs in Different Formulations across the Airway Epithelium In Vitro.

PLoS ONE 10 , e0135690, (2015)

Pulmonary drug delivery is characterized by short onset times of the effects and an increased therapeutic ratio compared to oral drug delivery. This delivery route can be used for local as well as for...

Increased Dose of Inhaled Corticosteroid versus Add-On Long-acting β-Agonist for Step-Up Therapy in Asthma.

Ann. Am. Thorac. Soc. 12 , 798-806, (2015)

Guidelines advocate adding long-acting β-agonist (LABA) to inhaled corticosteroid as the preferred step-up therapy to increasing inhaled corticosteroid dose for patients with uncontrolled asthma on in...

Atomoxetine prevents dexamethasone-induced skeletal muscle atrophy in mice.

J. Pharmacol. Exp. Ther. 351(3) , 663-73, (2014)

Skeletal muscle atrophy remains a clinical problem in numerous pathologic conditions. β2-Adrenergic receptor agonists, such as formoterol, can induce mitochondrial biogenesis (MB) to prevent such atro...

FORMOTEROL FUMARATE DIHYDRATE
Formoterol Fumarate
Formoterol Hemifumarate
N,O-Dibenzylated formoterol
NEP-IN-2
N-[5-[(1R)-Hydroxy-2-[[(1R)-methyl-2-(4-methoxyphenyl)ethyl](phenylmethyl)amino]ethyl]-2-(phenylmethoxy)phenyl]-formamide
(I(2)R,I R)-5-[[[3-[(Dimethylamino)carbonyl]phenyl]amino]carbonyl]-3,4-bis(4-fluorophenyl)-I(2),I-dihydroxy-1-(1-methylethyl)-1H-pyrrole-2-heptanoic acid
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine
N1-(2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinolin-8-yl)-N2-(pyridin-4-ylmethyl)oxalamide