Cortistatin 14

[ Molecular Formula ]:
C₈₁H₁₁₄N₂₀O₁₈S₂

[ Molecular Weight ]:
1721.01000

[ Exact Mass ]:
1719.79000

[ PSA ]:
675.86000

[ LogP ]:
3.12890

[ Storage condition ]:
−20°C

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

The cortical neuropeptide, cortistatin-14, impairs post-training memory processing.

Brain Res. 775 , 250-252, (1997)

Cortistatin-14, a neuropeptide, is present primarily in the cortex and hippocampus. In the hippocampus, cortistatin-14 inhibits pyramidal cell firing and co-exists with GABA. To determine if cortistat...

Cortistatin: a member of the somatostatin neuropeptide family with distinct physiological functions.

Brain Res. Brain Res. Rev. 33 , 228-241, (2000)

Cortistatin is a recently discovered neuropeptide relative of somatostatin named after its predominantly cortical expression and ability to depress cortical activity. Cortistatin-14 shares 11 of the 1...

Structural and compositional determinants of cortistatin activity.

J. Neurosci. 56 , 611-619, (1999)

Cortistatin-14 (CST-14) is a putative novel neuropeptide that shares 11 of its 14 residues with somatostatin-14 (SRIF-14), yet its effects on sleep physiology, locomotor behavior and hippocampal funct...

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