![]() Cortistatin 14 structure
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Common Name | Cortistatin 14 | ||
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CAS Number | 186901-48-4 | Molecular Weight | 1721.01000 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C81H114N20O18S2 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | N/A |
The cortical neuropeptide, cortistatin-14, impairs post-training memory processing.
Brain Res. 775 , 250-252, (1997) Cortistatin-14, a neuropeptide, is present primarily in the cortex and hippocampus. In the hippocampus, cortistatin-14 inhibits pyramidal cell firing and co-exists with GABA. To determine if cortistatin-14 would impair retention, saline or cortistatin-14 were... |
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Cortistatin: a member of the somatostatin neuropeptide family with distinct physiological functions.
Brain Res. Brain Res. Rev. 33 , 228-241, (2000) Cortistatin is a recently discovered neuropeptide relative of somatostatin named after its predominantly cortical expression and ability to depress cortical activity. Cortistatin-14 shares 11 of the 14 amino acids of somatostatin-14 yet their nucleotide seque... |
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Structural and compositional determinants of cortistatin activity.
J. Neurosci. 56 , 611-619, (1999) Cortistatin-14 (CST-14) is a putative novel neuropeptide that shares 11 of its 14 residues with somatostatin-14 (SRIF-14), yet its effects on sleep physiology, locomotor behavior and hippocampal function are different from those of somatostatin. We studied th... |
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Roles for NHERF1 and NHERF2 on the regulation of C3a receptor signaling in human mast cells.
PLoS ONE 7 , e51355, (2013) The anaphylatoxin C3a binds to the G protein coupled receptor (GPCR, C3aR) and activates divergent signaling pathways to induce degranulation and cytokine production in human mast cells. Adapter proteins such as the Na(+)/H(+) exchange regulatory factor (NHER... |
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