2-(o-tolylaminomethylene)malonic acid diethyl ester

Names

[ CAS No. ]:
19146-73-7

[ Name ]:
2-(o-tolylaminomethylene)malonic acid diethyl ester

[Synonym ]:
o-Toluidinomethylen-malonsaeure-diaethylester
o-toluidinomethylene-malonic acid diethyl ester

Chemical & Physical Properties

[ Density]:
1.15g/cm3

[ Boiling Point ]:
346ºC at 760 mmHg

[ Molecular Formula ]:
C15H19NO4

[ Molecular Weight ]:
277.31600

[ Flash Point ]:
163ºC

[ Exact Mass ]:
277.13100

[ PSA ]:
64.63000

[ LogP ]:
2.49000

[ Vapour Pressure ]:
5.95E-05mmHg at 25°C

[ Index of Refraction ]:
1.547

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Diethyl ethoxymethylenemalonate
  • o-Toluidine
  • Diethyl malonate

DownStream

  • Ethyl 4-chloro-8-methylquinoline-3-carboxylate
  • 8-Methyl-4-quinolinol
  • Ethyl 4-hydroxy-8-methyl-3-quinolinecarboxylate
  • 3-Quinolinecarboxylic acid, 1,4-dihydro-8-methyl-4-oxo-

Related Compounds

  • N1-(2-chlorobenzyl)-N2-(2-(dimethylamino)-2-(1-methyl-1H-indol-3-yl)ethyl)oxalamide
  • (4-(5-Methyl-1,3,4-thiadiazol-2-yl)piperidin-1-yl)(1-(methylsulfonyl)piperidin-4-yl)methanone
  • 1-(2-(4-(5-Methyl-1,3,4-thiadiazol-2-yl)piperidin-1-yl)-2-oxoethyl)pyrrolidine-2,5-dione
  • 5-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
  • 1-(4-(5-(5-methyl-1,2,4-oxadiazol-3-yl)pyridin-2-yl)piperazin-1-yl)-2-(1H-pyrazol-1-yl)ethanone
  • (4-(5-(5-Ethyl-1,2,4-oxadiazol-3-yl)pyridin-2-yl)piperazin-1-yl)(5-(furan-2-yl)isoxazol-3-yl)methanone
  • (4-(5-(5-ethyl-1,2,4-oxadiazol-3-yl)pyridin-2-yl)piperazin-1-yl)(5-methyl-1-phenyl-1H-pyrazol-4-yl)methanone
  • (4-(5-(5-Ethyl-1,2,4-oxadiazol-3-yl)pyridin-2-yl)piperazin-1-yl)(2-methoxypyridin-3-yl)methanone
  • (4-(5-(5-Ethyl-1,2,4-oxadiazol-3-yl)pyridin-2-yl)piperazin-1-yl)(thiophen-3-yl)methanone
  • (E)-3-(furan-2-yl)-1-(4-(5-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)pyridin-2-yl)piperazin-1-yl)prop-2-en-1-one
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