Lopinavir Metabolite M-1

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Names

[ CAS No. ]:
192725-39-6

[ Name ]:
Lopinavir Metabolite M-1

[Synonym ]:
(2S,3S,5S)-2-(2,6-dimethylphenoxyacetyl)amino-3-hydroxy-5-(2S-(1-tetrahydropyrimid-2,4-dionyl)-3-methyl-butanoyl)amino-1,6-diphenylhexane
(aS)-N-[(1S,3S,4S)-4-[[(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-a-(1-methylethyl)-2,4-dioxo-1(2H)-Pyrimidineacetami-de
(aS)-N-[(1S,3S,4S)-4-[[(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-a-(1-methylethyl)-2,4-dioxo-1(2H)-Pyrimidineacetami-d
4-Oxo-ABT-378

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₇H₄₆N₄O₆

[ Molecular Weight ]:
642.78400

[ Exact Mass ]:
642.34200

[ PSA ]:
137.07000

[ LogP ]:
5.63440

[ Index of Refraction ]:
1.582

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(2S,3S,5S)-2-(2,6-Dimethylphenoxyacetyl)amino-3-hydroxy-5-amino-1,6-diphenylhexane
tert-Butyl L-valinate
2,6-Dimethylphenoxyacetic acid
N-(3-Methoxy-3-oxopropyl)-L-valine tert-Butyl Ester
N-(3-Propanamido)-L-valine tert-Butyl Ester
(S)-2-(2,4-dioxotetrahydropyrimidin-1-yl)-3-methylbutyric acid tert-butyl ester