Tartrazine

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Names

[ CAS No. ]:
1934-21-0

[ Name ]:
Tartrazine

[Synonym ]:
Trisodium 5-oxo-1-(4-sulfonatophenyl)-4-[(E)-(4-sulfonatophenyl)diazenyl]-2,5-dihydro-1H-pyrazole-3-carboxylate
1310yellow
c.i.640
1H-Pyrazole-3-carboxylic acid, 2,5-dihydro-5-oxo-1-(4-sulfophenyl)-4-[(E)-2-(4-sulfophenyl)diazenyl]-, sodium salt (1:3)
EINECS 217-699-5
1H-Pyrazole-3-carboxylic acid, 4,5-dihydro-5-oxo-1-(4-sulfophenyl)-4-[(4-sulfophenyl)azo]-, trisodium salt
C16H9N4Na3O9S2
YELLOW 5
Tartrazin
TARTRAZINE
FD & C Yellow 5
y-4
3-carboxy-5-hydroxy-1-para-sulfophenyl-4-para-sulfophenylazopyrazole trisodium salt
FD & C Yellow No. 5
Food Yellow No. 4
TARTAZINE
tartarazine
E102
MFCD00148908
FD and C Yellow No. 5
Acid Yellow 23
1H-pyrazole-3-carboxylic acid, 2,5-dihydro-5-oxo-1-(4-sulfophenyl)-4-[(E)-(4-sulfophenyl)azo]-, trisodium salt
l-gelb2
Filter Yellow

Chemical & Physical Properties

[ Density]:
1.93 g/cm3 (20ºC)

[ Melting Point ]:
300ºC

[ Molecular Formula ]:
C16H9N4Na3O9S2

[ Molecular Weight ]:
534.36

[ PSA ]:
220.19000

[ LogP ]:
2.78190

[ Storage condition ]:
-20°C

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ6400000
CHEMICAL NAME :
Pyrazole-3-carboxylic acid, 5-hydroxy-1-(p-sulfophenyl)-4-(p-sulfophenyl)azo-, trisodium salt
CAS REGISTRY NUMBER :
1934-21-0
LAST UPDATED :
199710
DATA ITEMS CITED :
23
MOLECULAR FORMULA :
C16-H9-N4-O9-S2.3Na
MOLECULAR WEIGHT :
534.38
WISWESSER LINE NOTATION :
T5NNJ AR DSWO& CVO DNUNR DSWO& EQ &-NA- 3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human
DOSE/DURATION :
14 ug/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - paresthesis Musculoskeletal - changes in teeth and supporting structures
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
12750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
476 mg/kg/28D-C
TOXIC EFFECTS :
Behavioral - food intake (animal)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
18500 mg/kg
SEX/DURATION :
female 7-22 day(s) after conception lactating female 21 day(s) post-birth
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - blood and lymphatic systems (including spleen and marrow) Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) Reproductive - Effects on Newborn - behavioral
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
1280 mg/kg
SEX/DURATION :
female 7-14 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
20 gm/kg
SEX/DURATION :
female 7-14 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
TYPE OF TEST :
Specific locus test

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Mammal - species unspecified Fibroblast
DOSE/DURATION :
5 mg/L
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,461,1982 *** REVIEWS *** TOXICOLOGY REVIEW DICPBB Drug Intelligence and Clinical Pharmacy. (POB 42435, Cincinnati, OH 45242) V.3- 1969- Volume(issue)/page/year: 9,198,1975 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M2148 No. of Facilities: 2666 (estimated) No. of Industries: 32 No. of Occupations: 45 No. of Employees: 47875 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M2148 No. of Facilities: 15429 (estimated) No. of Industries: 95 No. of Occupations: 99 No. of Employees: 318163 (estimated) No. of Female Employees: 157622 (estimated)

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H317-H334

[ Precautionary Statements ]:
P261-P280-P342 + P311

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R42/43

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
UQ6400000

Precursor & DownStream

Precursor

DownStream

  • p-Phenylenediamine

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Related Compounds

  • tartrazine acid
  • Certolake Tartrazine
  • Tartrazine,3-ethyl ester
  • 2-(Trimethylsilyl)ethyl 4-(aminomethyl)-4-(phenylcarbamoyl)piperidine-1-carboxylate
  • Dazcapistat, (R)-
  • 3-Chlorodibenzo[b,d]selenophene
  • 6-(4-Cyclopropyl-1H-imidazol-1-yl)-2,3-dihydro-5-methyl-1H-isoindol-1-one
  • 4,4,5,5-Tetramethyl-2-(1-oxaspiro[5.5]undec-8-en-9-yl)-1,3,2-dioxaborolane
  • 2-(3,3-Dimethyl-2-oxaspiro[4.5]dec-7-en-8-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • 2-(1,5-Diethyl-8-oxabicyclo[3.2.1]oct-2-en-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • 1-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperidine-4-carbonitrile
  • 1-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-YL)pyrimidin-2-YL)piperidine-3-carbonitrile
  • (S)-(5-boc-6-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-3-yl)boronic acid pinacol ester
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