(4S)-4-Ethyl-4-hydroxy-9-methoxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

Suppliers

Names

[ CAS No. ]:
19685-10-0

[ Name ]:
(4S)-4-Ethyl-4-hydroxy-9-methoxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

[Synonym ]:
1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-9-methoxy-, (4S)-
(4S)-4-Ethyl-4-hydroxy-9-methoxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
10-methoxycamptothecin
10-MethoxycaMptothecine

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
773.1±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C21H18N2O5

[ Molecular Weight ]:
378.378

[ Flash Point ]:
421.4±32.9 °C

[ Exact Mass ]:
378.121582

[ PSA ]:
90.65000

[ LogP ]:
1.69

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.723

[ Storage condition ]:
2-8C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (4S)-4-ethyl-3,4-dihydroxy-9-methoxy-3,4-dihydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-14(12H)-one
  • 1-isocyano-4-methoxybenzene
  • (S)-4-Ethyl-4-hydroxy-6-iodo-3-oxo-7-propargyl-1H-pyrano[3,4-c]-8-pyridone
  • diazomethane
  • (S)-10-Hydroxycamptothecin
  • methyl iodide
  • Campathecin
  • Camptothecin N-oxide

DownStream

  • (S)-10-Hydroxycamptothecin
  • Topotecan hydrochloride
  • (4S)-4α-Ethyl-4-hydroxy-7-amino-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

Related Compounds

  • 3,5-dichloro-N,N-dimethylpyridin-2-amine
  • 5-Chloro-1H-indole-2-carboxylic acid ((1S,2S,4S)-6-chloro-1-cyclohexylmethyl-2-hydroxy-4-methylcarbamoyl-hept-6-enyl)-amide
  • 1-isopropyl-3-(trifluoromethyl)-1H-pyrazole-5-carboxylic acid
  • 2-{[(Benzyloxy)carbonyl]amino}-3-(3-hydroxyphenyl)propanoic acid
  • N-[(2R)-2-(Mercaptomethyl)-3-(2-methylphenyl)-1-oxopropyl]-L-methionine
  • 4-Isocyanato-2-methylbut-1-ene
  • N-[2-(Cyclohexyloxy)phenyl]methanesulfonamide
  • N-But-3-ynylcyclohexanamine;hydrochloride
  • 2,4,6-triiodo-5-[[[2-(1-methylethyl)-1,3-dioxan-5-yl]carbonyl]amino]-1,3-Benzenedicarbonyl dichloride
  • 5,8-Bis((2-hydroxyethylamino)propionamido)-1,4-dihydroxyanthracene-9,19-dione
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.