Sulfamethazine sodium salt

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Names

[ CAS No. ]:
1981-58-4

[ Name ]:
Sulfamethazine sodium salt

[Synonym ]:
MFCD00068333
Sodium sulfametazine
Sodium sulfamezathine
Bovibol
4-Amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide
Sodium [(4-aminophenyl)sulfonyl](4,6-dimethylpyrimidin-2-yl)azanide
sulfamethazine sodium
4-Amino-N-(4,6-dimethyl-2-pyrimidyl)benzenesulfonamide Sodium Salt
Sodium sulfamethiazine
sodium sulfamethazine
Benzenesulfonamide, 4-amino-N-(4,6-dimethyl-2-pyrimidinyl)-, sodium salt (1:1)
Sulfadimidine sodium
Sodium [(4-aminophenyl)sulfonyl](4,6-dimethyl-2-pyrimidinyl)azanide
sodium sulfadimidinato
sulphadimidine sodium
Sodium sulfamethamide
sulfamethazine sodium salt
Sodium sulphamezathine

Chemical & Physical Properties

[ Density]:
1.392g/cm3

[ Boiling Point ]:
526.2ºC at 760mmHg

[ Melting Point ]:
176ºC

[ Molecular Formula ]:
C12H13N4NaO2S

[ Molecular Weight ]:
300.312

[ Flash Point ]:
272.1ºC

[ Exact Mass ]:
300.065704

[ PSA ]:
97.56000

[ LogP ]:
2.99720

[ Appearance of Characters ]:
white to off-white

[ Vapour Pressure ]:
3.64E-11mmHg at 25°C

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
H2O: soluble50mg/mL

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WO9300000
CHEMICAL NAME :
Sulfanilamide, N(sup 1)-(4,6-dimethyl-2-pyrimidinyl)-, monosodium salt
CAS REGISTRY NUMBER :
1981-58-4
LAST UPDATED :
199701
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C12-H14-N4-O2-S.Na
MOLECULAR WEIGHT :
301.35
WISWESSER LINE NOTATION :
T6NJ CNJ BMR D2SZW &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1165 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MIMEAO Minerva Medica. (Edizioni Minerva Medica, Casella Postale 491, I-10126 Turin, Italy) V.1- 1909- Volume(issue)/page/year: 52,1789,1961
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
974 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 81,17,1944
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
699 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MIMEAO Minerva Medica. (Edizioni Minerva Medica, Casella Postale 491, I-10126 Turin, Italy) V.1- 1909- Volume(issue)/page/year: 52,1789,1961
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
605 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MIMEAO Minerva Medica. (Edizioni Minerva Medica, Casella Postale 491, I-10126 Turin, Italy) V.1- 1909- Volume(issue)/page/year: 52,1789,1961 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4891 No. of Facilities: 299 (estimated) No. of Industries: 2 No. of Occupations: 18 No. of Employees: 3501 (estimated) No. of Female Employees: 883 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
WO9300000

[ HS Code ]:
2935009090

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

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