Medronic Acid

Suppliers

Names

[ CAS No. ]:
1984-15-2

[ Name ]:
Medronic Acid

[Synonym ]:
MDP,Medronic acid
phosphonomethylphosphonic acid
MDP,Medronic acid,Methylenediphosphonic acid
methanediylbis(phosphonic acid)
MDP~Medronicacid
Medronic Acid
Methylenediphosphonic acid
Methylenebiphosphonic Acid
methylene biphosphonate
acide méthanediylbis(phosphonique)
Methanebisphosphonic Acid
Methanediphosphonic Acid
Medronic acid [USAN:BAN:INN]
METHYLENEBISPHOSPHONIC ACID
Medronic
methylenediphosphonate
Phosphonic acid, methylenebis-
EINECS 217-851-0
MDP
Methylenebis(phosphonic acid)
MFCD00002139
Methandiylbis(phosphonsäure)

Chemical & Physical Properties

[ Density]:
2.1±0.1 g/cm3

[ Boiling Point ]:
583.2±60.0 °C at 760 mmHg

[ Melting Point ]:
197-199 °C(lit.)

[ Molecular Formula ]:
CH₆O₆P₂

[ Molecular Weight ]:
176.002

[ Flash Point ]:
306.5±32.9 °C

[ Exact Mass ]:
175.963959

[ PSA ]:
134.68000

[ LogP ]:
-4.11

[ Vapour Pressure ]:
0.0±3.5 mmHg at 25°C

[ Index of Refraction ]:
1.550

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C: Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 3261 8/PG 3

[ WGK Germany ]:
-

[ RTECS ]:
SZ9138000

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2931900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2931900090

[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

Articles

Blau syndrome-associated Nod2 mutation alters expression of full-length NOD2 and limits responses to muramyl dipeptide in knock-in mice.

J. Immunol. 194(1) , 349-57, (2014)

The biochemical mechanism by which mutations in nucleotide-binding oligomerization domain containing 2 (NOD2) cause Blau syndrome is unknown. Several studies have examined the effect of mutations asso...

Involvement of Nod2 in the innate immune response elicited by malarial pigment hemozoin.

Microbes Infect. 17(3) , 184-94, (2015)

In malaria, the evidence concerning the nucleotide-binding, oligomerization domain (NOD) 2 (NOD2) receptor is fragmented and the stimuli that might activate NOD2 are not well characterized. We investi...

Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation.

Cell Death Differ. 22 , 1676-86, (2015)

Neuronal active Caspase-6 (Casp6) is associated with Alzheimer disease (AD), cognitive impairment, and axonal degeneration. Caspase-1 (Casp1) can activate Casp6 but the expression and functionality of...