Medronic Acid
Modify Date: 2024-01-02 19:43:26
Medronic Acid structure
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Common Name | Medronic Acid | ||
|---|---|---|---|---|
| CAS Number | 1984-15-2 | Molecular Weight | 176.002 | |
| Density | 2.1±0.1 g/cm3 | Boiling Point | 583.2±60.0 °C at 760 mmHg | |
| Molecular Formula | CH6O6P2 | Melting Point | 197-199 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 306.5±32.9 °C | |
| Symbol |
GHS05 |
Signal Word | Danger | |
Use of Medronic AcidMedronic Acid (Methylenediphosphonic acid) is a methylene-substituted bisphosphonate. Medronic acid has affinity for and adheres to the surface of hydroxyapatite crystals in the bone matrix. This agent accumulates at sites of osteoid mineralization and can be used, complexed with radioisotopes in bone imaging. |
| Name | medronic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Medronic Acid (Methylenediphosphonic acid) is a methylene-substituted bisphosphonate. Medronic acid has affinity for and adheres to the surface of hydroxyapatite crystals in the bone matrix. This agent accumulates at sites of osteoid mineralization and can be used, complexed with radioisotopes in bone imaging. |
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| Related Catalog | |
| References |
| Density | 2.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 583.2±60.0 °C at 760 mmHg |
| Melting Point | 197-199 °C(lit.) |
| Molecular Formula | CH6O6P2 |
| Molecular Weight | 176.002 |
| Flash Point | 306.5±32.9 °C |
| Exact Mass | 175.963959 |
| PSA | 134.68000 |
| LogP | -4.11 |
| Vapour Pressure | 0.0±3.5 mmHg at 25°C |
| Index of Refraction | 1.550 |
| Storage condition | 2-8°C |
| Symbol |
GHS05 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H314 |
| Precautionary Statements | P280-P305 + P351 + P338-P310 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | C: Corrosive; |
| Risk Phrases | R34 |
| Safety Phrases | S26-S36/37/39-S45 |
| RIDADR | UN 3261 8/PG 3 |
| WGK Germany | - |
| RTECS | SZ9138000 |
| Packaging Group | III |
| Hazard Class | 8 |
| HS Code | 2931900090 |
|
~97%
Medronic Acid CAS#:1984-15-2 |
| Literature: Rubino, Maria Teresa; Agamennone, Mariangela; Campestre, Cristina; Campiglia, Pietro; Cremasco, Viviana; Faccio, Roberta; Laghezza, Antonio; Loiodice, Fulvio; Maggi, Dariana; Panza, Emilia; Rossello, Armando; Tortorella, Paolo ChemMedChem, 2011 , vol. 6, # 7 p. 1258 - 1268 |
|
~93%
Medronic Acid CAS#:1984-15-2 |
| Literature: Bulman Page, Philip C.; McKenzie, Michael J.; Gallagher, James A. Synthetic Communications, 2002 , vol. 32, # 2 p. 211 - 218 |
|
~99%
Medronic Acid CAS#:1984-15-2 |
| Literature: Mohamady, Samy; Jakeman, David L. Journal of Organic Chemistry, 2005 , vol. 70, # 25 p. 10588 - 10591 |
|
~%
Medronic Acid CAS#:1984-15-2 |
| Literature: Journal of the American Chemical Society, , vol. 83, p. 1722 - 1726 |
|
~%
Medronic Acid CAS#:1984-15-2 |
| Literature: Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, , vol. 31, p. 153 - 157 |
|
~%
Medronic Acid CAS#:1984-15-2 |
| Literature: Phosphorus, Sulfur and Silicon and Related Elements, , vol. 161, p. 75 - 96 |
CAS#:16001-93-7| HS Code | 2931900090 |
|---|---|
| Summary | 2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0% |
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Blau syndrome-associated Nod2 mutation alters expression of full-length NOD2 and limits responses to muramyl dipeptide in knock-in mice.
J. Immunol. 194(1) , 349-57, (2014) The biochemical mechanism by which mutations in nucleotide-binding oligomerization domain containing 2 (NOD2) cause Blau syndrome is unknown. Several studies have examined the effect of mutations asso... |
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Involvement of Nod2 in the innate immune response elicited by malarial pigment hemozoin.
Microbes Infect. 17(3) , 184-94, (2015) In malaria, the evidence concerning the nucleotide-binding, oligomerization domain (NOD) 2 (NOD2) receptor is fragmented and the stimuli that might activate NOD2 are not well characterized. We investi... |
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Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation.
Cell Death Differ. 22 , 1676-86, (2015) Neuronal active Caspase-6 (Casp6) is associated with Alzheimer disease (AD), cognitive impairment, and axonal degeneration. Caspase-1 (Casp1) can activate Casp6 but the expression and functionality of... |
| MDP,Medronic acid |
| phosphonomethylphosphonic acid |
| MDP,Medronic acid,Methylenediphosphonic acid |
| methanediylbis(phosphonic acid) |
| MDP~Medronicacid |
| Medronic Acid |
| Methylenediphosphonic acid |
| Methylenebiphosphonic Acid |
| methylene biphosphonate |
| acide méthanediylbis(phosphonique) |
| Methanebisphosphonic Acid |
| Methanediphosphonic Acid |
| Medronic acid [USAN:BAN:INN] |
| METHYLENEBISPHOSPHONIC ACID |
| Medronic |
| methylenediphosphonate |
| Phosphonic acid, methylenebis- |
| EINECS 217-851-0 |
| MDP |
| Methylenebis(phosphonic acid) |
| MFCD00002139 |
| Methandiylbis(phosphonsäure) |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Medronic Acid
- Price: ￥2138.0/5g ￥548.0/1g ￥8538.0/25g
- Purity: 97.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Methylenediphosphonic acid
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: Methylenebisphosphonic acid
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
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Price: ￥550/10 mM * 1 mL in DMSO
Reference only. check more Medronic Acid price