Fmoc-L-propargylglycine

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Names

[ CAS No. ]:
198561-07-8

[ Name ]:
Fmoc-L-propargylglycine

[Synonym ]:
Fmoc-propargyl-Gly-OH
(S)-2-(Fmoc-amino)-4-pentynoic Acid
(2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-pentynoic acid
MFCD01075095
4-Pentynoic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2S)-
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)pent-4-ynoic acid
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-propargylglycine
Fmoc-Pra-OH
(S)-N-Fmoc-2-(2'-propynyl)glycine

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
576.7±50.0 °C at 760 mmHg

[ Melting Point ]:
175ºC

[ Molecular Formula ]:
C20H17NO4

[ Molecular Weight ]:
335.353

[ Flash Point ]:
302.6±30.1 °C

[ Exact Mass ]:
335.115753

[ PSA ]:
75.63000

[ LogP ]:
4.19

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.619

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Safety Phrases ]:
S24-S25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2S)-2-Amino-4-pentynoic acid
  • 9H-fluoren-9-ylmethyl 2,5-dioxopyrrolidine-1-carboxylate
  • Fmoc-Osu
  • TETRAMETHYLBIPHOSPHINE
  • (S)-2-(benzhydrylidene-amino)-pent-4-ynoic acid tert-butyl ester

DownStream

  • (S)-N-Fmoc-Allylglycine

Related Compounds

  • Fmoc-L-2,5,7-tri-tert-butyl-tryptophan
  • fmoc-l-3-benzothienylalanine
  • Fmoc-L-Ala-OBt
  • FMoc-L-3-Thienylalanine
  • Fmoc-L-homocystine
  • FMOC-L-INDOLINE-2-CARBOXYLIC ACID
  • benzyl N-(3-fluoro-4-hydroxyphenyl)carbamate
  • 2-[3-(4-benzylpiperazin-1-yl)-6-oxopyridazin-1(6H)-yl]-N-(2-phenylethyl)acetamide
  • N-(4-chlorophenyl)-2-{[3-(propan-2-yl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl]sulfanyl}acetamide
  • N-(1H-benzimidazol-2-yl)-2-[(furan-2-ylmethyl)amino]-1,3-thiazole-4-carboxamide
  • N-(1H-benzimidazol-2-yl)-2-[3-(2-fluorophenyl)-6-oxopyridazin-1(6H)-yl]acetamide
  • 2-[2-(3-methoxyphenyl)-1,3-thiazol-4-yl]-N-[(2Z)-5-(2-phenylethyl)-1,3,4-thiadiazol-2(3H)-ylidene]acetamide
  • 2-[2-(4-bromophenyl)-2-oxoethyl]-6-(2-fluorophenyl)pyridazin-3(2H)-one
  • 2-[3-(2-fluorophenyl)-6-oxopyridazin-1(6H)-yl]-N-[(2Z)-6-methoxy-1,3-benzothiazol-2(3H)-ylidene]acetamide
  • 2-[3-(2-fluorophenyl)-6-oxopyridazin-1(6H)-yl]-N-[(2Z)-6-(methylsulfonyl)-1,3-benzothiazol-2(3H)-ylidene]acetamide
  • N-(2-chlorobenzyl)-2-[(furan-2-ylmethyl)amino]-4-methyl-1,3-thiazole-5-carboxamide
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