N6-(2-Phenylethyl)adenosine

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Names

[ CAS No. ]:
20125-39-7

[ Name ]:
N6-(2-Phenylethyl)adenosine

[Synonym ]:
2-(hydroxymethyl)-5-[6-(2-phenylethylamino)purin-9-yl]oxolane-3,4-diol

Chemical & Physical Properties

[ Density]:
1.57g/cm3

[ Boiling Point ]:
723.5ºC at 760 mmHg

[ Molecular Formula ]:
C18H21N5O4

[ Molecular Weight ]:
371.39000

[ Flash Point ]:
391.3ºC

[ Exact Mass ]:
371.15900

[ PSA ]:
125.55000

[ LogP ]:
0.16540

[ Vapour Pressure ]:
5.72E-22mmHg at 25°C

[ Index of Refraction ]:
1.741

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 6-bromo-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)-9H-purine
  • 2-Phenylethanamine
  • 6-Chloropurine riboside
  • Carbon
  • Inosine
  • Tin(IV) chloride

DownStream

Articles

Not1 mediates recruitment of the deadenylase Caf1 to mRNAs targeted for degradation by tristetraprolin.

Nucleic Acids Res. 39 , 4373-86, (2011)

The carbon catabolite repressor protein 4 (Ccr4)-Negative on TATA (Not) complex controls gene expression at two levels. In the nucleus, it regulates the basal transcription machinery, nuclear receptor...

Exploring distal regions of the A3 adenosine receptor binding site: sterically constrained N6-(2-phenylethyl)adenosine derivatives as potent ligands.

Bioorg. Med. Chem. 12 , 2021-2034, (2004)

We synthesized phenyl ring-substituted analogues of N(6)-(1S,2R)-(2-phenyl-1-cyclopropyl)adenosine, which is highly potent in binding to the human A(3)AR with a Ki value of 0.63 nM. The effects of the...

Effects of adenosine receptor agonists and antagonists on audiogenic seizure-sensible DBA/2 mice.

Eur. J. Pharmacol. 371 , 137-145, (1999)

We have studied the effects of selective and non-selective adenosine receptor agonists and antagonists in audiogenic-seizure-sensitive DBA/2 mice, an animal model of generalized reflex epilepsy. With ...


More Articles

Related Compounds

  • (R)?-?PIA
  • N-(1-methyl-2-phenylethyl)adenosine
  • NPD9948
  • N6-(2-Hydroxyethyl)adenosine
  • N6-(2-methoxybenzyl)adenosine
  • N6-[2-(4-Aminophenyl)ethyl]adenosine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-methyl-N-(3-phenylpropyl)-1H-1,2,3-triazole-4-carboxamide
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • N-((1-cyclohexyl-1H-tetrazol-5-yl)methyl)-4-methoxybenzamide